Septa 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 48.90

Medicine Details

Category Details
Generic Cephradine
Company Doctors chemical works ltd
Also available as
Septa 500 mg capsule Septa 125 mg suspension

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Active against Staphylococci, Streptococci, E. coli, Klebsiella spp, and more
  • Semisynthetic broad-spectrum bactericidal antibiotic

Pharmacology

  • Main site of action is the cell wall of bacteria
  • Inhibits cross-linking process in peptidoglycan
  • Bactericidal antibiotic against gram-positive and gram-negative microorganisms
  • Sensitive to both penicillinase producing and nonproducing Staphylococci

Dosage & Administration

  • Oral and injectable administration
  • Dosage varies for adults, children, and elderly
  • Total daily dose based on type and severity of infection
  • Dosage adjustments required for renal impairment
  • Maximum daily dosage: 4 gm

Interaction

  • Concomitant use with nephrotoxic drugs may increase kidney damage
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Rare side effects include glossitis, dizziness, nausea, vomiting, diarrhea, and more

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Administer with caution to patients hypersensitive to penicillins
  • May cause false positive urine glucose results

Use in Special Populations

  • Recommended doses for renal impairment
  • Higher doses may be required for severe infections
  • Dosages should be continued after symptoms have resolved

Overdose Effects

  • Non-specific symptoms include nausea, vomiting, and diarrhea
  • Supportive treatment required
  • Gastric lavage may be necessary

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepare suspension
  • Reconstituted suspension should be used within specified days
  • Injection solutions retain potency for a limited time
  • Store at specified temperatures
  • Do not use after expiry date

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