Sicef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 88.00

Medicine Details

Category Details
Generic Cephradine
Company Silva pharmaceuticals ltd
Also available as
Sicef 500 mg capsule Sicef ds 250 mg suspension Sicef 125 mg pediatric drop

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Gram-positive bacteria
  • Gram-negative bacteria

Pharmacology

  • Bactericidal antibiotic
  • Broad spectrum antibiotic
  • Cell wall inhibiting action
  • Peptidoglycan inhibition
  • Osmotic pressure lysis

Dosage & Administration

  • Oral administration for adults and children
  • Urinary tract infections dosage
  • Respiratory tract infections dosage
  • Skin and soft tissue infections dosage
  • Maximum daily dosage
  • Injectable administration for adults and children
  • Prophylactic dosage

Interaction

  • Nephrotoxic drugs interaction
  • Renal toxicity risk
  • Diuretics enhanced renal toxicity
  • Probenecid enhanced renal toxicity

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Glossitis
  • Heartburn
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Vaginitis
  • Candida overgrowth
  • Blood disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen
  • Elevation of serum creatinine
  • Elevation of alanine aminotransferase
  • Elevation of aspartate aminotransferase
  • Elevation of total bilirubin
  • Elevation of alkaline phosphatase

Pregnancy & Lactation

  • Teratogenicity in animal studies
  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential dizziness

Precautions & Warnings

  • Superinfection risk
  • Care in patients hypersensitive to penicillins
  • Coombs’ testing result
  • False positive urine glucose result
  • Dosage adjustment for renal impairment
  • Lactose content warning

Use in Special Populations

  • Recommended doses for renal impairment
  • Chronic or severe infection higher doses
  • Duration of treatment
  • Monitoring requirement
  • Paediatric dosages

Overdose Effects

  • Non-specific symptoms
  • Nausea
  • Vomiting
  • Diarrhoea
  • Gastric upsets
  • Supportive treatment
  • Gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Fresh preparation for Suspension
  • Reconstituted Suspension usage timeline
  • Injection solutions usage timeline
  • Solution color variation
  • Expiry date
  • Keep out of reach of children
  • Dispense on prescription

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