Sinaceph 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 95.00

Medicine Details

Category Details
Generic Cephradine
Company Ibn sina pharmaceuticals ltd
Also available as
Sinaceph 250 mg capsule Sinaceph 500 mg capsule Sinaceph ds 250 mg suspension Sinaceph 125 mg pediatric drop Sinaceph 500 mg injection Sinaceph 1 gm injection

Indications

  • Gram-positive bacteria treatment
  • Gram-negative bacteria treatment
  • Respiratory tract infection treatment
  • Urinary tract infection treatment
  • Skin and soft tissue infection treatment

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process of bacterial cell wall

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment for elderly and patients with impaired renal or hepatic function

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Blood and lymphatic system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen and other parameters

Pregnancy & Lactation

  • No established safety in pregnancy
  • Caution in lactating mothers due to excretion in breast milk
  • Advice to caution about operating hazardous machinery

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Administration with care to patients hypersensitive to penicillins
  • Possible Coombs’ test positivity
  • Possible false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Avoidance in patients with rare hereditary problems of galactose intolerance

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Higher doses for chronic or severe infections
  • Bacteriological and clinical monitoring for urinary tract infections
  • Transfer from intramuscular/intravenous to oral treatment

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, and diarrhoea
  • Supportive treatment
  • Gastric lavage if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Expiration and storage of reconstituted suspension and injection solutions
  • Dispensing on prescription of a registered physician

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