Sinaceph DS 250 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 125.00

Medicine Details

Category Details
Generic Cephradine
Company Ibn sina pharmaceuticals ltd
Also available as
Sinaceph 250 mg capsule Sinaceph 500 mg capsule Sinaceph 125 mg suspension Sinaceph 125 mg pediatric drop Sinaceph 500 mg injection Sinaceph 1 gm injection

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptibility to specific microorganisms

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Cell wall inhibitor
  • Mechanism of action at the cellular level

Dosage & Administration

  • Oral administration for adults and children
  • Specific dosage for urinary tract infections, respiratory tract infections, and skin and soft tissue infections
  • Dosage for injectable administration in adults and children
  • Dosage adjustments for elderly and patients with impaired renal or hepatic function

Interaction

  • Interaction with nephrotoxic drugs such as aminoglycosides
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Contraindicated in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare side effects such as glossitis, heartburn, dizziness, nausea, and more
  • Rare blood and lymphatic system disorders
  • Rare immune system disorders
  • Rare psychiatric and nervous system disorders
  • Rare hepatobiliary disorders
  • Rare renal and urinary disorders
  • Rare investigations related side effects

Pregnancy & Lactation

  • Safety not established in pregnancy
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Care in patients hypersensitive to penicillins
  • Cephalosporin antibiotics and Coombs’ testing
  • Potential for false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Lactose content and contraindications for patients with specific hereditary problems

Use in Special Populations

  • Recommended doses for patients with renal impairment and on haemodialysis
  • Additional information for all patients
  • Caution in paediatric dosages

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, and diarrhoea
  • Treatment is mainly supportive

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Preparation and shelf life of Sinaceph DS Suspension
  • Shelf life of Sinaceph DS Injection solutions
  • Storage temperature impact on potency
  • Dispensing only on the prescription of a registered physician

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