Sinaceph 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 55.00

Medicine Details

Category Details
Generic Cephradine
Company Ibn sina pharmaceuticals ltd
Also available as
Sinaceph 250 mg capsule Sinaceph 500 mg capsule Sinaceph 125 mg suspension Sinaceph ds 250 mg suspension Sinaceph 500 mg injection Sinaceph 1 gm injection

Title and Categories

  • Sinaceph Antibiotic Medicine
  • First Generation Cephalosporin
  • Oral and Injectable Antibiotic
  • Bactericidal Antibiotic
  • Prescription Medicine
  • Semisynthetic Broad Spectrum Antibiotic

Dimensions

N/A

Color Options

  • N/A

Functions

  • Treats infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Inhibits cross-linking process in bacterial cell wall
  • Bactericidal action against microorganisms

Materials

  • Cephradine

Technical Specifications

  • Active against gram-positive and gram-negative microorganisms
  • Sensitive to both penicillinase producing and nonproducing staphylococci
  • Excreted in breast milk

Design Elements

  • N/A

Usability Features

  • Oral and Injectable administration
  • Recommended for adults, children, and the elderly
  • Suitable for patients with impaired renal or hepatic function
  • Use with caution in lactating mothers
  • Caution advised for operating hazardous machinery

Indications

  • Treats upper respiratory tract infections
  • Treats lower respiratory tract infections
  • Treats urinary tract infections
  • Treats skin and soft tissue infections

Dosage and Administration

  • Oral administration for adults, children, and elderly
  • Injectable administration for adults and children
  • Dosage adjustment required in renal impairment
  • Prolonged use may result in superinfection

Interaction

  • Concomitant use with nephrotoxic drugs may increase risk of kidney damage
  • Diuretics and probenecid enhance possibility of renal toxicity

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rarer effects like glossitis, dizziness, nausea, vomiting, etc.
  • Blood disorders, immune system disorders, psychiatric disorders, nervous system disorders, hepato-biliary disorders, renal and urinary disorders, investigative disorders.

Pregnancy and Lactation

  • Animal studies have not shown teratogenicity
  • Excreted in breast milk
  • Use with caution in lactating mothers
  • Caution advised for operating hazardous machinery

Precautions and Warnings

  • Caution in patients hypersensitive to penicillins
  • Cephalosporin antibiotics may cause positive result in Coombs’ testing
  • May cause false positive urine glucose result in Benedict’s or Fehling’s solution tests
  • Dosage adjustment necessary in renal impairment
  • Contains lactose; caution in patients with hereditary problems of galactose intolerance

Use in Special Populations

  • Recommended doses for patients with renal impairment and on haemodialysis
  • Higher doses may be required for chronic or severe infections
  • Treatment duration at least 2 to 3 days after symptoms have resolved or bacteria eradicated

Overdose Effects

  • Non-specific symptoms like nausea, vomiting, diarrhoea, and gastric upsets
  • Supportive treatment required
  • Gastric lavage may be necessary

Therapeutic Class

  • First Generation Cephalosporins

Storage Conditions

  • Suspension should be freshly prepared
  • Reconstituted suspension should be used within 7-14 days
  • Injectable solutions should be used within 2 hours at room temperature, retain potency for 12 hours at 5°C
  • Disposal as per regulations

Related Brands