Sinaceph 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 85.00

Medicine Details

Category Details
Generic Cephradine
Company Ibn sina pharmaceuticals ltd
Also available as
Sinaceph 250 mg capsule Sinaceph 500 mg capsule Sinaceph 125 mg suspension Sinaceph ds 250 mg suspension Sinaceph 125 mg pediatric drop Sinaceph 500 mg injection

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptible microorganisms
  • Gram-positive microorganisms susceptible to Sinaceph
  • Gram-negative microorganisms susceptible to Sinaceph

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacteria cell wall
  • Lysis of bacteria due to external osmotic pressure

Dosage & Administration

  • Dosage for adults in urinary tract infections
  • Dosage for adults in respiratory tract infections
  • Dosage for adults in skin and soft tissue infections
  • Dosage for children
  • Maximum daily dosage for children
  • Dosage for the elderly
  • Dosage for injectable administration in adults
  • Dosage for injectable administration in children

Interaction

  • Concomitant use of nephrotoxic drugs
  • Enhanced risk of kidney damage with diuretics and probenecid

Contraindications

  • Patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare side effects

Pregnancy & Lactation

  • Teratogenicity in animal studies
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administration to patients hypersensitive to penicillins
  • Cephalosporin antibiotics may cause a positive result in Coombs’ testing
  • Potential for false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Lactose content

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Additional Information for all patients
  • Special considerations for paediatric dosages

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Requirement for gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Shelf life of reconstituted Suspension
  • Shelf life of Sinaceph Injection solutions
  • Storage temperature for solutions
  • Variation in color of reconstituted solutions
  • Expiry date and storage precautions
  • Dispensing only on prescription

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