SK-cef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 95.00

Medicine Details

Category Details
Generic Cephradine
Company Eskayef pharmaceuticals ltd
Also available as
Sk cef 250 mg capsule Sk cef 500 mg capsule Sk cef ds 250 mg suspension Sk cef 125 mg pediatric drop Sk cef 500 mg injection Sk cef 1 gm injection

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in the cell wall of bacteria

Dosage & Administration

  • For oral administration in adults and children
  • Maximum daily dosage: 4 gm
  • Dosage adjustment necessary in renal impairment
  • Recommendations for patients on chronic, intermittent hemodialysis
  • Higher doses of up to 1 gm four times daily may be required for chronic or severe infections

Interaction

  • Concomitant use of nephrotoxic drugs may increase risk of kidney damage
  • Diuretics and probenecid enhance possibility of renal toxicity

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Limited to gastro-intestinal disturbances and hypersensitivity phenomena
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Investigations

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution advised in lactating mothers

Precautions & Warnings

  • Prolonged use may result in development of superinfection
  • Administered with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose results
  • Dosage adjustment necessary in renal impairment
  • Contains lactose

Use in Special Populations

  • Recommendations for patients not on hemodialysis
  • Recommendations for patients on chronic, intermittent hemodialysis
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required in chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, and diarrhea
  • Supportive treatment
  • Gastric lavage may be necessary if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • SK-cef Suspension should be freshly prepared
  • Reconstituted Suspension should be used within 7-14 days
  • Injection solutions should be used within 2 hours at room temperature
  • Retain potency for 12 hours when stored at 5°C
  • Reconstituted solutions may vary in color but does not affect potency
  • Keep out of the reach of children
  • To be dispensed only on the prescription of a registered physician

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