SK-cef 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 65.00

Medicine Details

Category Details
Generic Cephradine
Company Eskayef pharmaceuticals ltd
Also available as
Sk cef 250 mg capsule Sk cef 500 mg capsule Sk cef 125 mg suspension Sk cef ds 250 mg suspension Sk cef 500 mg injection Sk cef 1 gm injection

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacteria cell wall
  • Susceptibility to penicillinase producing and nonproducing staphylococci

Dosage & Administration

  • Recommended oral dosage for adults and children
  • Dose adjustment for elderly, renal, and hepatic impairment
  • Usual injectable doses for adults and children
  • Maximum daily dosage
  • Preoperative prophylaxis dosage

Interaction

  • Concomitant use of nephrotoxic drugs
  • Enhanced risk with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Potential blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric and nervous system disorders
  • Hepatobiliary and renal disorders
  • Elevation of blood urea nitrogen and serum creatinine

Pregnancy & Lactation

  • Lack of established safety in pregnancy
  • Excretion in breast milk
  • Caution for lactating mothers

Precautions & Warnings

  • Development of superinfection with prolonged use
  • Cross-sensitivity with penicillins
  • Positive result in Coombs’ testing
  • Potential for false positive urine glucose result
  • Lactose content caution for specific patients

Use in Special Populations

  • Recommended doses for patients with renal impairment or on haemodialysis
  • Dose adjustments for chronic or severe infections
  • Duration of treatment and monitoring requirements

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Need for gastric lavage in case of large ingestion

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension shelf life
  • Injection solution shelf life
  • Potency retention at different temperatures
  • Dispensing only with a prescription

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