SK-cef 500 mg/vial (IM/IV Injection)
500 mg vial: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of upper respiratory tract infections
- Treatment of lower respiratory tract infections
- Treatment of urinary tract infections
- Treatment of skin and soft tissue infections
Pharmacology
- Broad spectrum bactericidal antibiotic
- Active against gram-positive and gram-negative microorganisms
- Inhibition of cross-linking process in cell wall of bacteria
Dosage & Administration
- Oral administration for adults and children
- Injectable administration for adults and children
- Dosing adjustments in renal impairment
Interaction
- Concomitant use with nephrotoxic drugs
- Enhanced risk of renal toxicity with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Blood and lymphatic system disorders
- Immune system disorders
- Psychiatric disorders
- Nervous system disorders
- Hepatobiliary disorders
- Renal and urinary disorders
- Investigations
- Rare side effects
Pregnancy & Lactation
- No established safety in pregnancy
- Excreted in breast milk
- Caution in lactating mothers
Precautions & Warnings
- Prolonged use may result in superinfection
- Administer with care to patients hypersensitive to penicillins
- Potential positive result in Coombs’ testing
- Potential false positive urine glucose result
- Dosage adjustment in renal impairment
- Contains lactose
Use in Special Populations
- Renal impairment dosing recommendations
- Higher doses may be required for chronic or severe infections
- Treatment continuation for at least 2 to 3 days after symptoms have resolved
Overdose Effects
- Non-specific symptoms
- Supportive treatment
- Necessity of gastric lavage
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Reconstituted suspension expiry
- Injection solution expiry
- Retention of potency
- Safety precautions