SK-cef 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 65.00

Medicine Details

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in cell wall of bacteria

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosing adjustments in renal impairment

Interaction

  • Concomitant use with nephrotoxic drugs
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Investigations
  • Rare side effects

Pregnancy & Lactation

  • No established safety in pregnancy
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administer with care to patients hypersensitive to penicillins
  • Potential positive result in Coombs’ testing
  • Potential false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose

Use in Special Populations

  • Renal impairment dosing recommendations
  • Higher doses may be required for chronic or severe infections
  • Treatment continuation for at least 2 to 3 days after symptoms have resolved

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Necessity of gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension expiry
  • Injection solution expiry
  • Retention of potency
  • Safety precautions

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