SK-cef 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 85.00

Medicine Details

Category Details
Generic Cephradine
Company Eskayef pharmaceuticals ltd
Also available as
Sk cef 250 mg capsule Sk cef 500 mg capsule Sk cef 125 mg suspension Sk cef ds 250 mg suspension Sk cef 125 mg pediatric drop Sk cef 500 mg injection

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Gram-positive bacteria infections
  • Gram-negative bacteria infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in the cell wall of bacteria
  • Cell wall lysis due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage based on infection site and severity
  • Dosage adjustment in renal impairment

Interaction

  • Risk of kidney damage with concomitant use of nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Investigations

Pregnancy & Lactation

  • Not established safety in pregnancy
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Risk of cross-sensitivity between beta-lactam antibiotics
  • Positive urine glucose result with certain tests
  • Dosage adjustment in renal impairment
  • Lactose content caution for specific patient groups

Use in Special Populations

  • Dosage recommendation for renal impairment
  • Additional information for all patients
  • Paediatric dosages
  • Transfer from intramuscular/intravenous therapy to oral treatment

Overdose Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Gastric upsets

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension shelf life
  • Injection solutions shelf life
  • Storage conditions for potency retention
  • Handling instructions

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