SK-cef 1 gm/vial (IM/IV Injection)
1 gm vial: ৳ 85.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
- Gram-positive bacteria infections
- Gram-negative bacteria infections
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Active against both gram-positive and gram-negative microorganisms
- Inhibition of cross-linking process in the cell wall of bacteria
- Cell wall lysis due to external osmotic pressure
Dosage & Administration
- Oral administration for adults and children
- Injectable administration for adults and children
- Dosage based on infection site and severity
- Dosage adjustment in renal impairment
Interaction
- Risk of kidney damage with concomitant use of nephrotoxic drugs
- Enhanced renal toxicity with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Blood and lymphatic system disorders
- Immune system disorders
- Psychiatric disorders
- Nervous system disorders
- Hepatobiliary disorders
- Renal and urinary disorders
- Investigations
Pregnancy & Lactation
- Not established safety in pregnancy
- Excretion in breast milk
- Caution in lactating mothers
Precautions & Warnings
- Risk of superinfection with prolonged use
- Risk of cross-sensitivity between beta-lactam antibiotics
- Positive urine glucose result with certain tests
- Dosage adjustment in renal impairment
- Lactose content caution for specific patient groups
Use in Special Populations
- Dosage recommendation for renal impairment
- Additional information for all patients
- Paediatric dosages
- Transfer from intramuscular/intravenous therapy to oral treatment
Overdose Effects
- Nausea
- Vomiting
- Diarrhoea
- Gastric upsets
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension
- Reconstituted suspension shelf life
- Injection solutions shelf life
- Storage conditions for potency retention
- Handling instructions