Sidopin 5 mg (Tablet)
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Eskayef pharmaceuticals ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Influences myocardial cells
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
Dosage & Administration
- Usual dose of 5 mg once daily for hypertension
- Maximum dose of 10 mg once daily
- 5 to 10 mg for chronic stable or vasospastic angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No significant interaction with Digoxin
- No significant interaction with Cimetidine
- No significant alteration of Warfarin effect
- Food does not alter absorption rate
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Limited studies in pregnant women
- Risk to the fetus
- Unknown excretion in human milk
- Discontinuation of nursing recommended
Precautions & Warnings
- Hepatic impairment precautions
- Pregnancy and breastfeeding precautions
Use in Special Populations
- Dosage for children with hypertension
- No data on children under 6 years old
- Elderly dosage recommendations
- Normal dosage in renal impairment
- Caution in hepatic impairment
- Severe hepatic impairment dosage recommendations
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked and prolonged systemic hypotension
- Shock with fatal outcome
- Active cardiovascular support required
- Monitoring of cardiac and respiratory function
- Elevation of extremities
- Attention to fluid volume and urine output
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in a cool & dry place
- Protected from light