Supracef 500 mg (Capsule)

Unit Price: ৳ 15.00 (7 x 4: ৳ 420.00)

Strip Price: ৳ 60.00

Medicine Details

Category	Details
Generic	Cephradine
Company	Biopharma limited
Also available as	Supracef 250 mg capsule Supracef 125 mg suspension Supracef f 250 mg suspension Supracef 125 mg pediatric drop

Indications

Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
Upper respiratory tract infections
Lower respiratory tract infections
Urinary tract infections
Skin and soft tissue infections
Susceptible microorganisms
Sinusitis
Pharyngitis
Tonsillitis
Laryngo-tracheo bronchitis
Otitis media
Bronchitis
Pneumonia
Pyelonephritis
Abscess
Cellulitis
Furunculosis
Impetigo

Pharmacology

Semisynthetic broad spectrum bactericidal antibiotic
Active against gram-positive and gram-negative microorganisms
Inhibition of cross-linking process in cell wall of bacteria
Cell wall sensitive organism contains peptidoglycan
Lysis of bacteria due to external osmotic pressure

Dosage & Administration

Oral administration for adults
Oral administration for children
Maximum daily dosage of 4 gm
Dosage for injectable administration in adults
Dosage for injectable administration in children

Interaction

Concomitant use of nephrotoxic drugs
Enhanced risk of kidney damage with diuretics and probenecid

Contraindications

Known or suspected hypersensitivity to cephalosporins

Side Effects

Gastro-intestinal disturbances
Hypersensitivity phenomena
Skin reactions
Glossitis
Heartburn
Dizziness
Nausea
Vomiting
Diarrhoea
Abdominal pain
Vaginitis
Candida overgrowth
Blood disorders
Immune system disorders
Psychiatric disorders
Nervous system disorders
Hepatobiliary disorders
Renal and urinary disorders

Pregnancy & Lactation

No demonstrated teratogenicity in animal studies
Excretion in breast milk
Caution in lactating mothers
May cause dizziness

Precautions & Warnings

Risk of superinfection with prolonged use
Administer with care to patients hypersensitive to penicillins
Potential positive result in Coombs’ testing
Potential false positive urine glucose result
Dosage adjustment in renal impairment
Contains lactose

Use in Special Populations

Recommended doses for renal impairment
Higher doses for chronic or severe infections
Monitoring required for chronic urinary tract infections
Paediatric dosages not to exceed those for adults

Overdose Effects

Non-specific symptoms
Nausea
Vomiting
Diarrhoea
Gastric upsets
Supportive treatment
Gastric lavage if large amount ingested

Therapeutic Class

First generation Cephalosporins

Storage Conditions

Freshly prepared suspension
Reconstituted suspension to be used within 7-14 days
Injection solutions to be used within 2 hours at room temperature
Solutions retain potency for 12 hours at 5°C
Reconstituted solutions may vary in color
Keep out of the reach of children
To be dispensed only on prescription of a registered physician

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