Supracef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 90.00

Medicine Details

Category Details
Generic Cephradine
Company Biopharma limited
Also available as
Supracef 250 mg capsule Supracef 500 mg capsule Supracef f 250 mg suspension Supracef 125 mg pediatric drop

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process of bacteria's cell wall

Dosage & Administration

  • Oral administration for adults and children
  • Dosage based on infection site and severity
  • Injectable administration for adults and children
  • Dosage adjustment for renal impairment

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Administered with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result
  • Dosage adjustment necessary in renal impairment

Use in Special Populations

  • Recommended doses for renal impairment and haemodialysis
  • Higher doses may be required for chronic or severe infections

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, and diarrhoea
  • Supportive treatment required

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Suspension should be freshly prepared
  • Reconstituted Suspension should be used within 7-14 days
  • Injection solutions retain potency for 2-12 hours
  • Dispense only on the prescription of a registered physician

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