Supracef F 250 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 130.00

Medicine Details

Category Details
Generic Cephradine
Company Biopharma limited
Also available as
Supracef 250 mg capsule Supracef 500 mg capsule Supracef 125 mg suspension Supracef 125 mg pediatric drop

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections: sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis
  • Lower respiratory tract infections: bronchitis (acute and chronic), lobar pneumonia and bronchopneumonia
  • Urinary tract infections: cystitis, urethritis, pyelonephritis
  • Skin and soft tissue infections: abscess, cellulitis, furunculosis, impetigo

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking of the bacterial cell wall

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment necessary in renal impairment
  • Maximum daily dosage: 4 gm

Interaction

  • Concomitant use of nephrotoxic drugs may increase the risk of kidney damage
  • Diuretics and probenecid enhance the possibility of renal toxicity

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Glossitis, heartburn, dizziness, nausea, vomiting, diarrhoea, abdominal pain, vaginitis, candida overgrowth
  • Hematological, immune, psychiatric, nervous system, hepatobiliary, renal and urinary disorders

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution advised in lactating mothers

Precautions & Warnings

  • Prolonged use may result in the development of superinfection
  • Administered with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result

Use in Special Populations

  • Dosing adjustments in renal impairment
  • Higher doses may be required for chronic or severe infections
  • Continued treatment for at least 2 to 3 days after symptoms have resolved

Overdose Effects

  • Non-specific symptoms: nausea, vomiting, diarrhea, gastric upsets
  • Supportive treatment required

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Suspension should be freshly prepared
  • Reconstituted Suspension should be used within 7-14 days
  • Injection solutions should be used within 2 hours when kept at room temperature

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