Ultrasef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 90.27

Medicine Details

Category Details
Generic Cephradine
Company Jayson pharmaceuticals ltd
Also available as
Ultrasef 250 mg capsule Ultrasef 500 mg capsule Ultrasef 125 mg pediatric drop

Title and Categories

  • Ultrasef
  • Antibiotic
  • Oral Suspension
  • Injectable Solution
  • First Generation Cephalosporins

Pharmacological Action

  • Bactericidal
  • Inhibits cell wall cross-linking
  • Active against gram-positive and gram-negative microorganisms
  • Effective against penicillinase producing and non-producing staphylococci

Dosage and Administration

  • 500mg four times daily for urinary tract infections (adults)
  • 1g twice daily for urinary tract infections (adults)
  • 250 to 500mg four times daily for respiratory tract infections (adults)
  • 500mg to 1g twice daily for respiratory tract infections (adults)
  • 250 to 500mg four times daily for skin and soft tissue infections (adults)
  • 500mg to 1g twice daily for skin and soft tissue infections (adults)
  • 25 to 50mg/kg total daily dose for children
  • Maximum daily dosage of 4 gm
  • 2-4 gm daily in four equally divided doses for adults (injectable administration)
  • 50-100 mg/kg daily in four equally divided doses for children (injectable administration)

Interaction

Nephrotoxic drugs may increase risk of kidney damage when used concomitantly

Contraindications

Hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Glossitis
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Vaginitis
  • Candida overgrowth
  • Thrombocytopenia
  • Leucopenia
  • Fever
  • Serum sickness like reactions
  • Anaphylaxis
  • Psychiatric disorders
  • Fever
  • Hepatobiliary disorders
  • Reversible interstitial nephritis
  • Elevation of blood urea nitrogen
  • Elevation of serum creatinine
  • Elevation of alanine aminotransferase
  • Elevation of aspartate aminotransferase
  • Elevation of total bilirubin
  • Elevation of alkaline phosphatase

Pregnancy and Lactation

Caution advised, excreted in breast milk

Precautions and Warnings

  • Risk of superinfection with prolonged use
  • Careful administration to patients hypersensitive to penicillins
  • Potential false positive urine glucose result
  • Dosage adjustment required in renal impairment
  • Contains lactose (avoid in hereditary lactase deficiencies)

Use in Special Populations

  • Recommended doses for renal impairment
  • Caution in patients on haemodialysis
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring for chronic urinary tract infections
  • Paediatric dosages should not exceed those specified for adults

Overdose Effects

Non-specific symptoms: nausea, vomiting, diarrhoea, gastric upsets

Therapeutic Class

First Generation Cephalosporins

Storage Conditions

Freshly prepared suspension, expiry date, keep out of reach of children

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