Vecef 500 mg (Capsule)

Unit Price: ৳ 12.50 (24's pack: ৳ 300.00)

Medicine Details

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Main site of action is the cell wall of bacteria

Dosage & Administration

  • For oral and injectable administration
  • Different dosage for adults and children
  • Usual dose for adults
  • Maximum daily dosage
  • Dosage adjustment in renal impairment

Interaction

  • Concomitant use of nephrotoxic drugs may increase risk of kidney damage
  • Diuretics and probenecid enhance possibility of renal toxicity

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen, serum creatinine, alanine aminotransferase, and more

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administered with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose
  • Patients with rare hereditary problems should not take this medicine

Use in Special Populations

  • Recommended doses for patients with renal impairment and on hemodialysis
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required for chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms
  • Treatment is mainly supportive
  • Gastric lavage may be necessary if a large amount has been ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Vecef Suspension should be freshly prepared
  • Reconstituted Suspension should be used within 7-14 days
  • Injection solutions should be used within 2 hours at room temperature
  • Solutions retain potency for 12 hours when stored at 5°C

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