Vecef-DS 250 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 120.00

Medicine Details

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

Cephradine is a broad spectrum bactericidal antibiotic active against both gram-positive and gram-negative microorganisms.

Dosage & Administration

  • For oral administration - Adults:
    • Infections dosage based on severity
    • Maximum daily dosage: 4 gm
  • For oral administration - Children:
    • Total daily dose of 25 to 50mg/kg
    • Maximum daily dosage: 4 gm
  • For injectable administration - Adult:
    • Usual dose of 2-4 gm daily in four equally divided doses
    • Prophylaxis dose of 1-2 gm intramuscularly or intravenously
  • For injectable administration - Children:
    • Dose of 50-100 mg/kg daily in four equally divided doses
    • up to 300 mg/kg daily in severe infection

Interaction

Concomitant use of nephrotoxic drugs may increase the risk of kidney damage.

Contraindications

Should not be used in patients with known or suspected hypersensitivity to cephalosporins.

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood disorders
  • Serum sickness like reactions
  • Renal disorders
  • Liver enzyme disturbances

Pregnancy & Lactation

Safety in pregnancy not established, excreted in breast milk, caution in lactating mothers.

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administered with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Adjustment necessary in renal impairment
  • Regular bacteriological and clinical monitoring is required

Overdose Effects

Non-specific symptoms such as nausea, vomiting, and diarrhoea, treatment is mainly supportive.

Therapeutic Class

First generation Cephalosporins

Storage Conditions

Freshly prepared Suspension, Injection solutions retain potency for a certain duration, keep all medicines out of the reach of children.

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