Vecef 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 50.00

Medicine Details

Category Details
Generic Cephradine
Company Asiatic laboratories ltd
Also available as
Vecef 500 mg capsule Vecef 125 mg suspension Vecef ds 250 mg suspension

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacterial cell walls

Dosage & Administration

  • Oral administration for adults and children
  • Different dosage for urinary tract, respiratory tract, and skin infections
  • Dosage adjustment for elderly and patients with impaired renal or hepatic function
  • Injectable administration for adults and children
  • Prophylactic dose for preoperative use

Interaction

  • Increased risk of kidney damage when used concomitantly with nephrotoxic drugs
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare reactions including glossitis, heartburn, dizziness, nausea, vomiting, diarrhoea
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen, serum creatinine, liver enzymes

Pregnancy & Lactation

  • No established teratogenicity in animal studies
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Caution in patients hypersensitive to penicillins
  • Potential positive result in Coombs’ testing
  • Potential false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Contains lactose - caution in patients with specific hereditary problems

Use in Special Populations

  • Recommended doses for renal impairment
  • Additional information for all patients
  • Caution against exceeding pediatric dosages
  • Possibility of transfer from intramuscular/intravenous therapy to oral treatment

Overdose Effects

  • Non-specific symptoms of nausea, vomiting, and gastric upsets
  • Supportive treatment and gastric lavage if necessary

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Usage timeframe for reconstituted suspension
  • Retention of potency for injection solutions
  • Variation in color of reconstituted solutions
  • Disclaimer for use beyond expiry date
  • Keep out of reach of children
  • Dispensing only on prescription

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