Wincef 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 80.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | The white horse pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of Upper respiratory tract infections
- Treatment of Lower respiratory tract infections
- Treatment of Urinary tract infections
- Treatment of Skin and soft tissue infections
- Susceptible microorganisms - Gram-positive bacteria
- Susceptible microorganisms - Gram-negative bacteria
Pharmacology
- Type of antibiotic - Bactericidal
- Activity against Gram-positive microorganisms
- Activity against Gram-negative microorganisms
- Site of action - Bacterial cell wall
- Mechanism of action - Inhibition of cross-linking process in cell wall
Dosage & Administration
- Recommended dosage for oral administration in adults
- Recommended dosage for oral administration in children
- Maximum daily dosage for oral administration in children
- Recommended dosage for injectable administration in adults
- Recommended dosage for injectable administration in children
Interaction
- Potential interaction with nephrotoxic drugs
- Enhanced risk of renal toxicity with diuretics
- Enhanced risk of renal toxicity with probenecid
Contraindications
- Contraindicated in patients with known or suspected hypersensitivity to cephalosporins
Side Effects
- Common side effects - Gastro-intestinal disturbances
- Risk of hypersensitivity reactions
- Rare side effects - Glossitis, heartburn, dizziness, nausea, vomiting
- Rare side effects - Joint pains, skin rashes, oedema
- Rare side effects - Blood disorders, immune system disorders, psychiatric disorders
- Rare side effects - Nervous system disorders, liver and urinary disorders
Pregnancy & Lactation
- Safety in pregnancy not established
- Excretion in breast milk
- Caution in lactating mothers
- Potential for causing dizziness
Precautions & Warnings
- Risk of superinfection with prolonged use
- Risk of cross-sensitivity in patients hypersensitive to penicillins
- Potential positive result in Coombs’ testing
- Potential for false positive urine glucose result
- Necessary dosage adjustment in renal impairment
- Lactose content caution for patients with specific conditions
Use in Special Populations
- Recommended doses for patients with renal impairment not on haemodialysis
- Recommended doses for patients on chronic, intermittent haemodialysis
- Need for regular bacteriological and clinical monitoring in chronic urinary tract infections
- Duration of treatment for infections with haemolytic streptococci
Overdose Effects
- Non-specific symptoms of overdose - Nausea, vomiting, diarrhea
- Supportive treatment for overdose
- Need for gastric lavage in case of large ingestion
Therapeutic Class
- Belongs to the first generation Cephalosporins
Storage Conditions
- Fresh preparation of Suspension
- Storage duration for reconstituted Suspension at room temperature
- Storage duration for reconstituted Suspension in a refrigerator
- Usage duration for Injection solutions at room temperature
- Usage duration for Injection solutions at 5°C
- Variation in color of reconstituted solutions - Potency unaffected
- Dispensing on the prescription of a registered physician
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