Zecef 500 mg (Capsule)

Unit Price: ৳ 15.00 (7 x 4: ৳ 420.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Cephradine
Company Gaco pharmaceuticals ltd
Also available as
Zecef 125 mg suspension Zecef 125 mg pediatric drop

Title

  • Zecef

Categories

  • Medicine
  • Antibiotic
  • Pharmaceutical

Description

  • Cephradine is a semisynthetic broad spectrum bactericidal antibiotic
  • Active against infections caused by both gram-positive and gram-negative microorganisms
  • Main site of action of Cephradine is the cell wall of bacteria
  • Excreted in breast milk and should be used with caution in lactating mothers
  • Should not be used in patients with known or suspected hypersensitivity to cephalosporins
  • Limited side effects essentially to gastro-intestinal disturbances and on occasions to hypersensitivity phenomena

Color Options

  • White powder for injection
  • Suspension may vary in color from light to straw yellow

Functions

  • Treats infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Bactericidal antibiotic action
  • Inhibits cross-linking process in the cell wall of bacteria
  • Prevents the emergence of resistant organisms

Materials

  • Cephradine
  • Peptidoglycan
  • Lactose

Technical Specifications

  • Dosage adjustment necessary in renal impairment
  • Doses for special populations like children and elderly
  • Storage conditions for Suspension and Injection solutions

Design Elements

  • First generation Cephalosporins
  • Broad spectrum antibiotic
  • Cell wall inhibitor

Usability Features

  • Oral administration
  • Injectable administration
  • Dosage adjustment in renal or hepatic function
  • Freshly prepared Suspension
  • Reconstituted Suspension and Injection solutions usage timeframes

Dimensions

  • Dosage varies for different age groups
  • Total daily dosage specified
  • Maximum daily dosage
  • Reconstituted solutions may vary in color

Interaction

  • Concomitant use of nephrotoxic drugs may increase the risk of kidney damage
  • Diuretics and probenecid enhance the possibility of renal toxicity

Contraindications

  • Not to be used in known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Skin reactions
  • Rare blood and lymphatic system disorders
  • Psychiatric and nervous system disorders
  • Hepatobiliary and renal disorders

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administered with care to patients hypersensitive to penicillins
  • May cause a false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose

Use in Special Populations

  • Renal Impairment dosages for patients on haemodialysis
  • Higher doses for chronic or severe infections
  • Regular bacteriological and clinical monitoring for urinary tract infections
  • Paediatric dosages should not exceed those specified for adults

Overdose Effects

  • Non-specific symptoms include nausea, vomiting, and diarrhoea
  • Treatment is mainly supportive

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Suspension usage timeframes
  • Injection solution usage timeframes
  • Variation in color of reconstituted solutions
  • Expiry date importance

Indications

  • Treats upper respiratory tract infections
  • Treats lower respiratory tract infections
  • Treats urinary tract infections
  • Treats skin and soft tissue infections

Pharmacology

  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking in the cell wall of bacteria

Dosage & Administration

  • Dosage for adults and children
  • Dosage for urinary, respiratory, and skin infections
  • Dosage for elderly and patients with impaired renal or hepatic function

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