Zecef 500 mg (Capsule)
Unit Price: ৳ 15.00 (7 x 4: ৳ 420.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Gaco pharmaceuticals ltd |
| Also available as |
Title
- Zecef
Categories
- Medicine
- Antibiotic
- Pharmaceutical
Description
- Cephradine is a semisynthetic broad spectrum bactericidal antibiotic
- Active against infections caused by both gram-positive and gram-negative microorganisms
- Main site of action of Cephradine is the cell wall of bacteria
- Excreted in breast milk and should be used with caution in lactating mothers
- Should not be used in patients with known or suspected hypersensitivity to cephalosporins
- Limited side effects essentially to gastro-intestinal disturbances and on occasions to hypersensitivity phenomena
Color Options
- White powder for injection
- Suspension may vary in color from light to straw yellow
Functions
- Treats infections caused by sensitive Gram-positive and Gram-negative bacteria
- Bactericidal antibiotic action
- Inhibits cross-linking process in the cell wall of bacteria
- Prevents the emergence of resistant organisms
Materials
- Cephradine
- Peptidoglycan
- Lactose
Technical Specifications
- Dosage adjustment necessary in renal impairment
- Doses for special populations like children and elderly
- Storage conditions for Suspension and Injection solutions
Design Elements
- First generation Cephalosporins
- Broad spectrum antibiotic
- Cell wall inhibitor
Usability Features
- Oral administration
- Injectable administration
- Dosage adjustment in renal or hepatic function
- Freshly prepared Suspension
- Reconstituted Suspension and Injection solutions usage timeframes
Dimensions
- Dosage varies for different age groups
- Total daily dosage specified
- Maximum daily dosage
- Reconstituted solutions may vary in color
Interaction
- Concomitant use of nephrotoxic drugs may increase the risk of kidney damage
- Diuretics and probenecid enhance the possibility of renal toxicity
Contraindications
- Not to be used in known or suspected hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Skin reactions
- Rare blood and lymphatic system disorders
- Psychiatric and nervous system disorders
- Hepatobiliary and renal disorders
Pregnancy & Lactation
- Safety in pregnancy not established
- Excreted in breast milk
- Caution in lactating mothers
Precautions & Warnings
- Prolonged use may result in superinfection
- Administered with care to patients hypersensitive to penicillins
- May cause a false positive urine glucose result
- Dosage adjustment in renal impairment
- Contains lactose
Use in Special Populations
- Renal Impairment dosages for patients on haemodialysis
- Higher doses for chronic or severe infections
- Regular bacteriological and clinical monitoring for urinary tract infections
- Paediatric dosages should not exceed those specified for adults
Overdose Effects
- Non-specific symptoms include nausea, vomiting, and diarrhoea
- Treatment is mainly supportive
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Suspension usage timeframes
- Injection solution usage timeframes
- Variation in color of reconstituted solutions
- Expiry date importance
Indications
- Treats upper respiratory tract infections
- Treats lower respiratory tract infections
- Treats urinary tract infections
- Treats skin and soft tissue infections
Pharmacology
- Active against both gram-positive and gram-negative microorganisms
- Inhibits cross-linking in the cell wall of bacteria
Dosage & Administration
- Dosage for adults and children
- Dosage for urinary, respiratory, and skin infections
- Dosage for elderly and patients with impaired renal or hepatic function