Vasopin 5 mg (Tablet)

Unit Price: ৳ 4.02 (3 x 10: ৳ 120.60)
Strip Price: ৳ 40.20

Medicine Details

Category Details
Generic Amlodipine besilate
Company Silva pharmaceuticals ltd
Also available as

Indications

  • Essential hypertension
  • Angina pectoris
  • Vasospastic angina

Pharmacology

  • Dihydropyridine calcium-channel blocker
  • Long duration of action
  • Vasodilation
  • Reduced peripheral resistance
  • Increased coronary blood flow

Dosage & Administration

  • Usual dose 5 mg once daily
  • Maximum dose 10 mg once daily
  • May be taken without regard to meals

Interaction

  • Potentially hazardous interactions with p-blockers
  • No interaction with Digoxin
  • No interaction with Cimetidine
  • No significant alteration with Warfarin
  • No alteration by food intake

Contraindications

  • Hypersensitivity to dihydropyridine derivatives
  • Pregnancy

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema
  • Gastrointestinal disturbances
  • Increased micturition frequency
  • Lethargy
  • Eye pain
  • Mental depression
  • Ischaemic chest pain
  • Excessive fall in blood pressure
  • Rashes
  • Fever
  • Abnormalities in liver function

Pregnancy & Lactation

  • Pregnancy Category C
  • Benefit justifies potential risk to the fetus
  • Recommendation to discontinue nursing while administered

Precautions & Warnings

  • Precaution in patients with hepatic impairment
  • Precaution during pregnancy and breastfeeding

Use in Special Populations

  • Specific dosing for children with hypertension from 6 years to 17 years of age
  • Effect on blood pressure in patients less than 6 years of age is not known
  • Normal dosage regimens recommended in the elderly
  • No correlation between renal impairment and plasma concentrations
  • Dose selection cautions in hepatic impairment

Overdose Effects

  • Excessive peripheral vasodilatation
  • Reflex tachycardia
  • Systemic hypotension
  • Clinical management guidelines for amlodipine overdosage

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Keep out of reach of children
  • Store in a cool & dry place
  • Protected from light

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