Zenaf 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 82.00

Medicine Details

Category Details
Generic Cephradine
Company Cosmic pharma ltd
Also available as
Zenaf 500 mg capsule Zenaf 125 mg pediatric drop

Title

  • Zenaf

Categories

  • Medicine
  • Antibiotic
  • Pharmaceutical

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in cell wall of bacteria

Dosage & Administration

  • For oral administration:
    • Different doses for adults and children
    • Maximum daily dosage of 4 gm
    • Dosage adjustment necessary in renal impairment
  • For injectable administration:
    • Usual dose for adults
    • Dose for children
    • Prophylactic dose for preoperative use

Interaction

  • Concomitant use of nephrotoxic drugs may increase the risk of kidney damage
  • Diuretics and probenecid enhance renal toxicity

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Glossitis
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Renal and urinary disorders
  • Liver enzyme disturbances

Pregnancy & Lactation

  • Animal studies show no teratogenicity
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Administer with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result with certain tests
  • Contains lactose - caution in patients with rare hereditary problems of galactose intolerance

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required for chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms
  • Treatment is mainly supportive

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension usage timeframe
  • Retain potency for injection solutions
  • Dispensed only on prescription

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