Vesocal 10 mg (Tablet)
Unit Price: ৳ 8.03 (3 x 10: ৳ 240.90)
Strip Price: ৳ 80.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Rangs pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Reflex increase in coronary heart rate
Dosage & Administration
- Usual dose 5 mg once daily for hypertension
- Maximum dose 10 mg once daily for hypertension
- Dosage range 5-10 mg for angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction between Vesocal and Digoxin
- No interaction between Vesocal and Cimetidine
- No significant alteration of Warfarin effect by Vesocal
- Food does not alter absorption of Vesocal
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Rashes
- Fever
- Abnormalities in liver function
- Excessive fall in blood pressure
- Ischaemic chest pain
- Transient blindness
Pregnancy & Lactation
- Pregnancy Category C
- Use only if potential benefit justifies potential risk to the fetus
- Recommendation to discontinue nursing while Amlodipine is administered
Precautions & Warnings
- Precaution in patients with hepatic impairment
- Precaution during pregnancy and breastfeeding
Use in Special Populations
- Different dosing for children and elderly
- Normal dosage regimens recommended for elderly
- Normal dosage recommended for renal impairment
- Careful dose selection for mild to moderate hepatic impairment
- Lower initial dose recommended for severe hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked and prolonged systemic hypotension
- Clinical management of hypotension
- Gastric lavage
- Use of charcoal to reduce absorption rate
- Unlikelihood of benefit from dialysis
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Store in a cool & dry place
- Protected from light