Clocef 500 mg (Capsule)
Unit Price: ৳ 45.00 (8's pack: ৳ 360.00)
Medicine Details
Category | Details |
---|---|
Generic | Cefaclor monohydrate |
Company | Amico laboratories ltd |
Also available as |
Indications
- Treatment of respiratory tract infections
- Treatment of otitis media
- Treatment of pharyngitis and tonsillitis
- Treatment of urinary tract infections
- Treatment of skin and skin structure infections
Pharmacology
- Stability against b-lactamase inactivation
- Broad spectrum of activity
- Active against various organisms in vitro
Dosage & Administration
- Adult dose: 250 mg every 8 hours
- Maximum adult dosage: 4 g/day
- Pediatric dose: 20 mg/kg/day in divided doses every 8 hours
- Renal impairment dosage adjustments not usually required
- Haemodialysis dosage recommendations
Interaction
- False-positive reaction for glucose in the urine
- Reports of increased anticoagulant effect
- Regular monitoring of prothrombin time recommended
Contraindications
- Known allergy to Cephalosporin group of antibiotics
Side Effects
- Gastro-intestinal symptoms
- Transient hepatitis and cholestatic jaundice
- Fever, abdominal pain, superinfection, renal dysfunction, toxic nephropathy
- Hemorrhage, elevated LDH, pancytopenia
Pregnancy & Lactation
- Use during pregnancy only if clearly needed
- Small amounts detected in mother's milk
- Effect on nursing infants not known
- Caution for nursing women
Precautions & Warnings
- Prescribing in absence of proven or strongly suspected bacterial infection unlikely to provide benefit
- Prolonged use may result in overgrowth of nonsusceptible organisms
- Renal excretion inhibited by Probenecid
- Caution in individuals with a history of gastrointestinal disease
- Determine hypersensitivity reactions before therapy
- Administer cautiously to penicillin-sensitive patients
Overdose Effects
- Nausea, vomiting, epigastric distress, and diarrhea
Therapeutic Class
- Second generation Cephalosporins
Reconstitution
- Instructions for reconstitution of powder for suspension and pediatric drops
Storage Conditions
- Store at room temperature and protect from light
- Reconstituted suspension can be used within specific timeframes based on storage temperature
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