Clocef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 175.00

Medicine Details

Category Details
Generic Cefaclor monohydrate
Company Amico laboratories ltd
Also available as
Clocef 500 mg capsule

Product Title

  • Clocef

Categories

  • Medicine
  • Antibiotic
  • Cephalosporin

Description

  • Indicated for respiratory tract infections, otitis media, pharyngitis, tonsillitis, urinary tract infections, skin and skin structure infections
  • Active against Alpha and beta haemolytic Streptococci, Staphylococci, Streptococcus pneumoniae, Branhamella catarrhalis, Escherichia coli, Proteus mirabilis, Klebsiella species, Haemophilus influenzae
  • Adult dosage of 250 mg every 8 hours, with a maximum dosage of 4 g/day
  • Pediatric dosage of 20 mg/kg/day, with a maximum dosage of 1 g/day
  • Contraindicated in patients with known allergy to Cephalosporins
  • Possible side effects include diarrhea, nausea, vomiting, transient hepatitis, cholestatic jaundice, fever, abdominal pain, renal dysfunction, toxic nephropathy, hemorrhage, elevated LDH, and pancytopenia
  • Caution advised during pregnancy and lactation

Infections Treated

  • Respiratory tract infections
  • Otitis media
  • Pharyngitis
  • Tonsillitis
  • Urinary tract infections
  • Skin and skin structure infections

Organisms Active Against

  • Alpha and beta haemolytic Streptococci
  • Staphylococci
  • Streptococcus pneumoniae
  • Branhamella catarrhalis
  • Escherichia coli
  • Proteus mirabilis
  • Klebsiella species
  • Haemophilus influenzae

Dosage

  • Adult dose of 250 mg every 8 hours, may be doubled for severe infections
  • Pediatric dose of 20 mg/kg/day, raised to 40 mg/kg/day for serious infections
  • Dosage adjustments for renal impairment

Contraindications

  • Known allergy to Cephalosporins

Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Transient hepatitis
  • Cholestatic jaundice
  • Fever
  • Abdominal pain
  • Renal dysfunction
  • Toxic nephropathy
  • Hemorrhage
  • Elevated LDH
  • Pancytopenia

Pregnancy & Lactation

  • Caution advised

Overdose Effects

  • Nausea
  • Vomiting
  • Epigastric distress
  • Diarrhea

Therapeutic Class

  • Second generation Cephalosporins

Reconstitution

  • Instructions for preparing powder for suspension
  • Instructions for preparing pediatric drops

Storage Conditions

  • Store at room temperature
  • Protect from light
  • After reconstitution, use within 7-14 days based on storage temperature
  • Keep bottle tightly closed

Interaction

  • Potential for false-positive reaction for glucose in urine with certain tests
  • Increased anticoagulant effect with oral anticoagulants
  • Regular monitoring of prothrombin time recommended when administering with anticoagulants

Dosage & Administration

  • Adult and pediatric dosages
  • Special considerations for renal impairment
  • Administration during haemodialysis
  • Geriatric use

Precautions & Warnings

  • Avoid use in the absence of bacterial infection or prophylactic indication
  • Potential for overgrowth of nonsusceptible organisms with prolonged use
  • Caution in individuals with a history of gastrointestinal disease
  • Inquire about previous hypersensitivity reactions before therapy
  • Administer cautiously to penicillin-sensitive patients

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