Xelcard 5 mg (Tablet)

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Indications

  • Essential hypertension
  • Angina pectoris
  • Vasospastic angina

Mode of Action

  • Vasodilation
  • Reduced peripheral resistance
  • Increased coronary blood flow
  • Increase in myocardial oxygen supply

Dosage & Administration

  • Usual dose is 5 mg once daily for hypertension
  • Usual dose is 5-10 mg for angina
  • May be taken without regard to meals

Interaction

  • Potentially hazardous interactions with p-blockers
  • No interaction with Digoxin
  • No interaction with Cimetidine
  • No significant alteration with Warfarin
  • Food does not alter absorption

Contraindications

  • Hypersensitivity to dihydropyridine derivatives
  • Pregnant woman

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema
  • Gastrointestinal disturbances
  • Increased micturition frequency
  • Lethargy
  • Eye pain
  • Mental depression
  • Ischaemic chest pain
  • Excessive fall in blood pressure
  • Rashes
  • Fever
  • Abnormalities in liver function

Pregnancy & Lactation

  • Category C for pregnancy
  • Use during pregnancy only if benefit outweighs risk
  • Discontinue nursing while administered

Precautions & Warnings

  • Caution in hepatic impairment
  • Caution during pregnancy and breastfeeding

Use in Special Populations

  • Dosage for children with hypertension
  • Elderly patients well-tolerated
  • Normal dosage in renal impairment
  • Caution in hepatic impairment

Overdose Effects

  • Symptoms include excessive peripheral vasodilatation and reflex tachycardia
  • Marked and prolonged systemic hypotension
  • Management with active cardiovascular support
  • Use of vasoconstrictor
  • Intravenous calcium gluconate may be beneficial
  • Gastric lavage may be worthwhile
  • Use of charcoal to reduce absorption rate
  • Dialysis is not likely to be of benefit

Therapeutic Class

Calcium-channel blockers

Storage Conditions

  • Keep out of reach of children
  • Store in a cool & dry place
  • Protected from light

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