Xelcard 5 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate |
Company | Healthcare pharmaceuticals ltd |
Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Mode of Action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Increase in myocardial oxygen supply
Dosage & Administration
- Usual dose is 5 mg once daily for hypertension
- Usual dose is 5-10 mg for angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration with Warfarin
- Food does not alter absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant woman
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Category C for pregnancy
- Use during pregnancy only if benefit outweighs risk
- Discontinue nursing while administered
Precautions & Warnings
- Caution in hepatic impairment
- Caution during pregnancy and breastfeeding
Use in Special Populations
- Dosage for children with hypertension
- Elderly patients well-tolerated
- Normal dosage in renal impairment
- Caution in hepatic impairment
Overdose Effects
- Symptoms include excessive peripheral vasodilatation and reflex tachycardia
- Marked and prolonged systemic hypotension
- Management with active cardiovascular support
- Use of vasoconstrictor
- Intravenous calcium gluconate may be beneficial
- Gastric lavage may be worthwhile
- Use of charcoal to reduce absorption rate
- Dialysis is not likely to be of benefit
Therapeutic Class
Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in a cool & dry place
- Protected from light