Clorocef 500 mg (Capsule)

Unit Price: ৳ 40.00 (3 x 4: ৳ 480.00)
Strip Price: ৳ 160.00

Medicine Details

Category Details
Generic Cefaclor monohydrate
Company Ibn sina pharmaceuticals ltd
Also available as
Clorocef 250 mg capsule Clorocef 125 mg suspension Clorocef 125 mg pediatric drop

Indications

  • Respiratory tract infections
  • Otitis media
  • Pharyngitis
  • Tonsillitis
  • Urinary tract infections
  • Pyelonephritis
  • Cystitis
  • Skin and skin structure infections

Pharmacology

  • Stability against b-lactamase inactivation
  • Broad spectrum of activity
  • Activity against Streptococci
  • Activity against Staphylococci
  • Activity against Escherichia coli
  • Activity against Haemophilus influenzae
  • Activity against Proteus mirabilis
  • Activity against Klebsiella species
  • Effective in the eradication of Streptococci from the nasopharynx

Dosage & Administration

  • Adult dosage: 250 mg every 8 hours
  • Severe infections may require doubled doses
  • Maximum dosage of 4 g/day
  • Paediatric dosage: 20 mg/kg/day
  • Paediatric dosage for serious infections: 40 mg/kg/day
  • Maximum paediatric dosage: 1 g/day
  • Safety and effectiveness for infants under 1 month not established
  • Dosage adjustments for renal impairment
  • Dosage recommendations for haemodialysis patients
  • No identified differences in responses between elderly and younger patients

Interaction

  • False-positive reaction for glucose in the urine
  • Reports of increased anticoagulant effect
  • Rare reports of increased prothrombin time

Contraindications

  • Allergy to Cephalosporin group of antibiotics

Side Effects

  • Gastro-intestinal symptoms
  • Diarrhea
  • Nausea
  • Vomiting
  • Transient hepatitis
  • Cholestatic jaundice
  • Fever
  • Abdominal pain
  • Superinfection
  • Renal dysfunction
  • Toxic nephropathy
  • Hemorrhage
  • Elevated LDH
  • Pancytopenia

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution in use during pregnancy
  • Detection of Cefaclor in mother's milk
  • Unknown effect on nursing infants

Precautions & Warnings

  • Prescription in absence of proven bacterial infection unlikely to provide benefit
  • Prolonged use may result in overgrowth of nonsusceptible organisms
  • Inhibition of renal excretion by Probenecid
  • Prescription caution in individuals with history of gastrointestinal disease
  • Inquiry about previous hypersensitivity reactions
  • Caution in penicillin-sensitive patients

Overdose Effects

  • Nausea
  • Vomiting
  • Epigastric distress
  • Diarrhea

Therapeutic Class

  • Second generation Cephalosporins

Reconstitution

  • Shake well before mixing with water
  • Preparation of suspension
  • Preparation of pediatric drops
  • Validity of suspension after preparation
  • Validity of pediatric drops after preparation

Storage Conditions

  • Storage at room temperature
  • Protection from light
  • Validity of reconstituted suspension

Related Brands