Loracef 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 201.00
Medicine Details
Category | Details |
---|---|
Generic | Cefaclor monohydrate |
Company | Square pharmaceuticals plc |
Also available as |
Title
- Loracef
Categories
- Medicine
- Antibiotic
- Cephalosporin
Description
- Indicated in the treatment of respiratory tract infections, otitis media, pharyngitis, tonsillitis, urinary tract infections, skin and skin structure infections
- Active against various organisms such as Streptococci, Staphylococci, Escherichia coli, Haemophilus influenzae, Proteus mirabilis, Klebsiella species
- Dosage varies for adults and children
- Contraindicated in patients with known allergy to the Cephalosporin group of antibiotics
- Potential side effects include gastrointestinal symptoms, transient hepatitis, cholestatic jaundice, fever, abdominal pain, superinfection, renal dysfunction, toxic nephropathy, hemorrhage, elevated LDH, pancytopenia
- Caution advised during pregnancy and lactation
- Prolonged use may result in the overgrowth of nonsusceptible organisms
- Antibiotics, including Cephalosporins, should be prescribed with caution in individuals with a history of gastrointestinal disease
- Shake well before reconstitution and store at room temperature, protect from light
Dimensions
Color Options
Functions
- Treatment of infections
- Active against specific organisms
- Dosage administration
- Contraindications
- Side effects monitoring
- Caution during pregnancy and lactation
- Precautions for overdose
- Reconstitution guidelines
- Storage instructions
Materials
Technical Specifications
- Active ingredient: Cefaclor
- Therapeutic class: Second generation Cephalosporins
Design Elements
Usability Features
- Variety of dosage forms - Capsules, Powder for Suspension, Pediatric Drops
Other Features
- Interaction with oral anticoagulants
- Effect on nursing infants
- Renal impairment considerations
- Geriatric use
Indications
- Respiratory tract infections
- Otitis media
- Pharyngitis
- Tonsillitis
- Urinary tract infections
- Skin and skin structure infections
Pharmacology
- Stability against beta-lactamase inactivation
- Broad spectrum of activity
- Effective in the eradication of Streptococci from the nasopharynx
Dosage & Administration
- Adult dose: 250 mg every 8 hours
- Pediatric dose: 20 mg/kg/day divided every 8 hours
- Renal impairment adjustments
- Haemodialysis considerations
- Geriatric use
Interaction
- False-positive reaction for glucose in the urine with certain tests
- Potential increased anticoagulant effect when administered concomitantly with oral anticoagulants
- Recommendation for regular monitoring of prothrombin time
Contraindications
- Known allergy to Cephalosporin group of antibiotics
Side Effects
- Gastro-intestinal symptoms
- Transient hepatitis
- Cholestatic jaundice
- Fever
- Abdominal pain
- Superinfection
- Renal dysfunction
- Toxic nephropathy
- Hemorrhage
- Elevated LDH
- Pancytopenia
Pregnancy & Lactation
- Use during pregnancy only if clearly needed
- Detection in mother's milk
- Caution during nursing
Precautions & Warnings
- Avoid use in absence of proven or strongly suspected bacterial infection
- Prolonged use may result in the overgrowth of nonsusceptible organisms
- Inhibition of renal excretion by Probenecid
- Prescribed with caution in individuals with a history of gastrointestinal disease
- Careful inquiry into previous hypersensitivity reactions
- Caution in penicillin-sensitive patients
Overdose Effects
- Nausea
- Vomiting
- Epigastric distress
- Diarrhea
Therapeutic Class
- Second generation Cephalosporins
Reconstitution
- Guidelines for reconstitution of Powder for Suspension and Pediatric Drops
- Shake well before mixing water
- Storage duration after reconstitution
Storage Conditions
- Store at room temperature
- Protect from light
- Storage duration after reconstitution
Related Brands
- Loracef 125 mg/1.25 ml (Pediatric Drops) - square-pharmaceuticals-plc
- Navacef 500 mg (Capsule) - navana-pharmaceuticals-ltd
- Navacef 125 mg/5 ml (Powder for Suspension) - navana-pharmaceuticals-ltd
- Navacef 125 mg/1.25 ml (Pediatric Drops) - navana-pharmaceuticals-ltd
- Oticlor 125 mg/5 ml (Powder for Suspension) - incepta-pharmaceuticals-ltd