Loracef 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 135.00

Medicine Details

Category Details
Generic Cefaclor monohydrate
Company Square pharmaceuticals plc
Also available as
Loracef 125 mg suspension

Product Title

  • Loracef

Categories

  • Medicine
  • Antibiotic
  • Cephalosporin

Description

  • Loracef is a second generation cephalosporin antibiotic used to treat various infections, including respiratory tract infections, otitis media, pharyngitis, tonsillitis, urinary tract infections, and skin and skin structure infections.

Size Options

  • Capsule
  • Powder for Suspension
  • Pediatric Drops

Dosage Forms

  • Capsule
  • Powder for Suspension
  • Pediatric Drops

Dosage Strengths

  • 250 mg
  • 20 mg/kg
  • 40 mg/kg
  • 0.625 ml
  • 1 tsp
  • 2 tsp
  • 1 g
  • 250-500 mg

Recommended Dosage

  • 250 mg every 8 hours for adults
  • 20 mg/kg/day in divided doses every 8 hours for pediatric patients over 1 month
  • 40 mg/kg/day for serious infections in pediatric patients
  • 0.5 tsp three times daily for children under 1 year
  • 1 tsp three times daily for children 1-5 years
  • 2 tsp three times daily for children over 5 years

Maximum Dosage

  • 4 g/day for adults
  • 1 g/day for pediatric patients
  • 250-500 mg every 6 hours during interdialytic period for patients undergoing haemodialysis

Renal Impairment

  • Cefaclor may be administered in the presence of impaired renal function. Dose adjustments for patients with moderate or severe renal impairment are not usually required.

Geriatric Use

  • Clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.

Interactions

  • May show false-positive reaction for glucose in the urine with tests that use Benedict's solution, Fehling's solutions.
  • Reports of increased anticoagulant effect and increased prothrombin time in patients receiving Loracef and oral anticoagulants concomitantly.

Contraindications

  • Contraindicated in patients with known allergy to the Cephalosporin group of antibiotics.

Side Effects

  • Gastro-intestinal symptoms such as diarrhea, nausea, vomiting
  • Transient hepatitis and cholestatic jaundice
  • Fever, abdominal pain, superinfection, renal dysfunction, toxic nephropathy, hemorrhage, elevated LDH, pancytopenia

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Cautious use during pregnancy and lactation

Precautions & Warnings

  • Prescribing in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
  • Prolonged use may result in the overgrowth of nonsusceptible organisms.
  • Caution should be exercised in patients with history of gastrointestinal disease, particularly colitis.
  • Careful inquiry should be made to determine previous hypersensitivity reactions to Loracef, Cephalosporins, Penicillins or other drugs.
  • Administer cautiously to penicillin-sensitive patients.

Overdose Effects

  • Nausea, vomiting, epigastric distress, diarrhea

Therapeutic Class

  • Second generation Cephalosporins

Reconstitution

  • Instructions for preparing suspension and pediatric drops

Storage Conditions

  • Store at room temperature and protect from light
  • Reconstituted suspension can be used within 7-14 days if stored at room temperature or in refrigerator

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