Navacef 125 mg/5 ml (Powder for Suspension)

60 ml bottle: ৳ 130.87

Medicine Details

Indications

  • Respiratory tract infections
  • Otitis media
  • Pharyngitis
  • Tonsillitis
  • Urinary tract infections
  • Pyelonephritis
  • Cystitis
  • Skin and skin structure infections

Pharmacology

  • Second generation cephalosporin antibiotic
  • Stability against b-lactamase inactivation
  • Broad spectrum of activity
  • Active against various organisms

Dosage & Administration

  • Adult dose of capsule
  • Pediatric dose for powder for suspension & pediatric drops
  • Dose adjustments in renal impairment
  • Dosage for patients undergoing haemodialysis
  • Safety and effectiveness for infants less than 1 month

Interaction

  • False-positive reaction for glucose in the urine
  • Increased anticoagulant effect with oral anticoagulants
  • Regular monitoring of prothrombin time

Contraindications

  • Known allergy to Cephalosporin group of antibiotics

Side Effects

  • Gastro-intestinal symptoms
  • Transient hepatitis
  • Cholestatic jaundice
  • Fever
  • Abdominal pain
  • Superinfection
  • Renal dysfunction
  • Toxic nephropathy
  • Hemorrhage
  • Elevated LDH
  • Pancytopenia

Pregnancy & Lactation

  • Use during pregnancy only if clearly needed
  • Detection in mother's milk
  • Effect on nursing infants

Precautions & Warnings

  • Prescribing in the absence of proven bacterial infection
  • Prolonged use and the overgrowth of nonsusceptible organisms
  • Inhibition of renal excretion by Probenecid
  • Prescription with caution in individuals with a history of gastrointestinal disease
  • Previous hypersensitivity reactions inquiry
  • Caution in penicillin-sensitive patients
  • Caution in patients with demonstrated allergy

Overdose Effects

  • Nausea
  • Vomiting
  • Epigastric distress
  • Diarrhea

Therapeutic Class

  • Second generation cephalosporins

Reconstitution

  • Preparation of suspension, shaking, and mixing water
  • Usability period after reconstitution

Storage Conditions

  • Storage at room temperature
  • Protection from light
  • Usability period after reconstitution

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