Navacef 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 135.00

Medicine Details

Title

  • Navacef

Categories

  • Antibiotic
  • Medicine
  • Healthcare

Description

  • Cefaclor is a second generation cephalosporin antibiotic with a broad spectrum of activity.

Indications

  • Respiratory tract infections
  • Otitis media
  • Pharyngitis
  • Tonsillitis
  • Urinary tract infections
  • Skin and skin structure infections

Pharmacology

  • Stability against b-lactamase inactivation
  • Active against Alpha and beta haemolytic Streptococci, Staphylococci, Streptococcus pneumoniae, Branhamella catarrhalis, Escherichia coli, Proteus mirabilis, Klebsiella species, Haemophilus influenzae

Dosage and administration

  • Adult dose: 250 mg every 8 hours
  • Pediatric dose: 20 mg/kg/day
  • Dosage adjustments in renal impairment
  • Administration in patients undergoing haemodialysis
  • Use in geriatric patients

Interaction

  • False-positive reaction for glucose in urine with certain tests
  • Potential interaction with oral anticoagulants like Warfarin

Contraindications

  • Known allergy to the Cephalosporin group of antibiotics

Side effects

  • Gastro-intestinal symptoms
  • Transient hepatitis
  • Cholestatic jaundice
  • Fever
  • Superinfection
  • Renal dysfunction
  • Hemorrhage
  • Elevated LDH
  • Pancytopenia

Pregnancy and lactation

  • Use during pregnancy only if clearly needed
  • Cautious use during nursing

Precautions and warnings

  • Prescribing in proven or strongly suspected bacterial infection
  • Prolonged use may result in overgrowth of nonsusceptible organisms
  • Inhibition of renal excretion by Probenecid
  • Cautious prescription in individuals with a history of gastrointestinal disease
  • Inquiry about previous hypersensitivity reactions
  • Cautious use in penicillin-sensitive patients

Overdose effects

  • Nausea
  • Vomiting
  • Epigastric distress
  • Diarrhea

Therapeutic class

  • Second generation Cephalosporins

Reconstitution

  • Instructions for reconstitution of powder for suspension and pediatric drops

Storage conditions

  • Storage at room temperature
  • Protection from light
  • Storage duration for reconstituted suspension

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