Oticef 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 200.60
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefaclor monohydrate |
| Company | Alco pharma ltd |
| Also available as |
Title
- Oticef
Categories
- Medicine
- Antibiotic
- Cephalosporin
Description
- Oticef is a second generation cephalosporin antibiotic used in the treatment of respiratory tract infections, otitis media, pharyngitis, tonsillitis, urinary tract infections, skin and skin structure infections, etc.
- It is active against a range of organisms including Streptococci, Staphylococci, Branhamella catarrhalis, Escherichia coli, Proteus mirabilis, Klebsiella species, and Haemophilus influenzae.
DosageOptions
- Capsule
- Powder for suspension
- Pediatric drops
DosageInstructions
- Adult dose: 250 mg every 8 hours, with potential doubling for severe infections
- Pediatric dose: 20 mg/kg/day in divided doses every 8 hours, with potential increase in case of serious infections
- Specific dosages for children based on age and weight
- Dosage adjustments for patients with renal impairment
- Recommendations for patients undergoing haemodialysis
- Geriatric use considerations
InteractionWithOtherDrugs
- Potential false-positive reaction for glucose in urine tests
- Possible increased anticoagulant effect when used concomitantly with oral anticoagulants, necessitating regular monitoring of prothrombin time
Contraindications
- Known allergy to the Cephalosporin group of antibiotics
SideEffects
- Gastrointestinal symptoms such as diarrhea, nausea, vomiting
- Rare cases of transient hepatitis, cholestatic jaundice, fever, abdominal pain, superinfection, renal dysfunction, toxic nephropathy, hemorrhage, elevated LDH, pancytopenia
PregnancyAndLactationConsiderations
- Lack of adequate and well-controlled studies in pregnant women
- Detection of small amounts in mother's milk
- Caution advised when administered to nursing women
PrecautionsAndWarnings
- Avoid in the absence of a proven or strongly suspected bacterial infection
- Risk of developing drug-resistant bacteria
- Possibility of overgrowth of nonsusceptible organisms with prolonged use
- Inhibition of renal excretion by Probenecid
- Prescribed with caution in individuals with a history of gastrointestinal disease
- Inquiry into previous hypersensitivity reactions to Cephalosporins, Penicillins or other drugs before therapy
- Administration with caution to penicillin-sensitive patients
OverdoseEffects
- Nausea, vomiting, epigastric distress, diarrhea
TherapeuticClass
- Second generation Cephalosporins
ReconstitutionInstructions
- Shaking the bottle well before mixing the water for powder for suspension and pediatric drops
- Storage conditions and shelf life after reconstitution
StorageConditions
- Room temperature storage
- Protection from light
- Shelf life after reconstitution