Oticef 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 125.38

Medicine Details

Indications

  • Respiratory tract infections
  • Pneumonia
  • Bronchitis
  • Otitis media
  • Pharyngitis
  • Tonsillitis
  • Urinary tract infections
  • Pyelonephritis
  • Cystitis
  • Skin and skin structure infections

Pharmacology

  • Second generation cephalosporin antibiotic
  • Stability against beta-lactamase inactivation
  • Broad spectrum of activity
  • Active against various organisms

Dosage & Administration

  • Capsule: Adult dose
  • Powder for suspension & Pediatric drops: Children
  • Dosage for different age groups
  • Dosage adjustments for renal impairment
  • Dosage for patients undergoing hemodialysis
  • Geriatric use

Interaction

  • False-positive reaction for glucose in urine
  • Interaction with oral anticoagulants
  • Increased anticoagulant effect
  • Recommendation for regular monitoring of prothrombin time

Contraindications

  • Known allergy to cephalosporin group of antibiotics

Side Effects

  • Gastrointestinal symptoms
  • Transient hepatitis
  • Cholestatic jaundice
  • Fever
  • Abdominal pain
  • Superinfection
  • Renal dysfunction
  • Toxic nephropathy
  • Hemorrhage
  • Elevated LDH
  • Pancytopenia

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Caution for use during pregnancy
  • Detection in mother's milk
  • Unknown effect on nursing infants
  • Caution for use in nursing women

Precautions & Warnings

  • Avoid use in absence of bacterial infection
  • Risk of developing drug-resistant bacteria
  • Prolonged use may result in overgrowth of nonsusceptible organisms
  • Caution in individuals with history of gastrointestinal disease
  • Careful inquiry for previous hypersensitivity reactions
  • Caution for use in penicillin-sensitive patients

Overdose Effects

  • Nausea
  • Vomiting
  • Epigastric distress
  • Diarrhea

Therapeutic Class

  • Second generation cephalosporins

Reconstitution

  • Instructions for reconstituting powder for suspension
  • Shaking the bottle well
  • Preparation of suspension and pediatric drops
  • Storage duration after reconstitution

Storage Conditions

  • Room temperature storage
  • Protection from light
  • Storage duration after reconstitution
  • Tightly closed bottle

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