Amdova 5 mg+10 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Amlodipine besilate atorvastatin
Company Beximco pharmaceuticals ltd

Title

  • Amlodipine and Atorvastatin Tablets

Categories

  • Cardiovascular Medication
  • Cholesterol Lowering Medication

Description

  • Combination of Amlodipine Besilate BP equivalent to 5 mg Amlodipine and Atorvastatin calcium INN equivalent to 10 mg Atorvastatin
  • Indicated for hypertension, chronic stable angina, hypercholesterolemia, and multiple risk factors for CHD
  • Contains Amlodipine, a calcium channel blocker, and Atorvastatin, a statin (HMG-CoA reductase inhibitor)
  • Dosage ranges for Amlodipine from 5-10 mg once daily, for Atorvastatin from 10 to 80 mg once daily
  • Contraindicated in patients with known hypersensitivity to Amlodipine or Atorvastatin

Dimensions

N/A

Color Options

N/A

Functions

  • Reduces blood pressure
  • Lowers total cholesterol, LDL-cholesterol, apolipoprotein B, and triglyceride levels
  • Treats hypertension, chronic stable angina, hypercholesterolemia, and multiple risk factors for CHD

Materials

Amlodipine Besilate, Atorvastatin calcium

Technical Specifications

  • Amlodipine Dosage:
    • 5 mg
    • 10 mg
  • Atorvastatin Dosage:
    • 10 mg
    • 20 mg
    • 40 mg
    • 80 mg

Design Elements

Tablets

Usability Features

  • Oral administration
  • Can be used alone or in combination with other antihypertensive or antianginal drugs
  • Can be administered with or without food

Dosage & Administration

  • Amlodipine:
    • Usual initial dose - 5 mg once daily
    • Maximum dose - 10 mg once daily
  • Atorvastatin:
    • Recommended starting dose - 10 mg daily
    • Dosage range - 10 to 80 mg once daily

Interaction

  • Atorvastatin Interactions:
    • Cyclosporine
    • Fibric acid derivatives
    • Niacin
    • Erythromycin
    • Azole antifungals
  • Amlodipine Interactions:
    • Beta-blockers
    • ACE inhibitors
    • Alpha-1-blockers
    • Diuretics

Contraindications

  • Amlodipine: Known hypersensitivity to Amlodipine
  • Atorvastatin: Hypersensitivity to any component, active liver disease

Side Effects

  • Amlodipine:
    • Acute hypotension
    • Caution in severe aortic stenosis
    • Caution in patients with heart failure
  • Atorvastatin:
    • Elevation in serum creatine phosphokinase levels
    • Uncomplicated myalgia
    • Constipation
    • Headache

Pregnancy & Lactation

Safety not established during pregnancy, not recommended during breastfeeding

Precautions & Warnings

  • Increased Angina and/or Myocardial Infarction: Rarely reported
  • Liver Dysfunction: Associated with biochemical abnormalities of liver function

Use in Special Populations

  • Pediatrics: Safety and efficacy not established in children
  • Geriatrics: Efficacy and safety similar to general population

Therapeutic Class

Anti-anginal & lipid lowering drugs

Storage Conditions

  • Cool and dry place
  • Protect from light and moisture
  • Keep out of reach of children

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