Axefur 250 mg (Tablet)

Unit Price: ৳ 25.00 (12's pack: ৳ 300.00)

Medicine Details

Indications

  • Treatment of infections caused by sensitive bacteria
  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
  • Lower respiratory tract infections including pneumoniae caused by various bacteria
  • Acute bacterial exacerbation of chronic bronchitis and secondary bacterial infections of acute bronchitis caused by certain bacteria
  • Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
  • Urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus
  • Gonorrhoea caused by Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi

Pharmacology

  • Broad-spectrum bactericidal activity against a wide range of common pathogens
  • Good stability to bacterial β-lactamase
  • Active against ampicillin-resistant and amoxycillin-resistant strains

Dosage

  • Dosage for adolescents and adults (13 years and older)
  • Dosage for paediatric patients (3 months to 12 years)
  • Dosage for parenteral administration in adults, children, and neonates
  • Specific dosages for various infections such as pharyngitis/tonsillitis, acute bacterial maxillary sinusitis, chronic bronchitis, skin infections, urinary tract infections, pneumonia, MDR Typhoid Fever, Early Lyme disease, meningitis, and bone and joint infections

Administration

  • Use of freshly reconstituted solution recommended
  • Recommended potency maintenance duration at room temperature and at 5° C

Interaction

  • No potentially hazardous interactions reported

Contraindications

  • Contraindicated in patients with known allergy to Cephalosporins

Side Effects

  • Adverse effects occurred infrequently
  • Effects reported include rashes and gastrointestinal disturbances
  • Prolonged use may result in the overgrowth of non-susceptible organisms

Pregnancy & Lactation

  • US FDA pregnancy category B
  • No adequate and well-controlled studies in pregnant women
  • Caution advised during lactation

Precautions & Warnings

  • Caution advised for patients receiving concurrent treatment with potent diuretics and with a history of colitis
  • Possible safe administration to patients hypersensitive to penicillin
  • Likely not a problem at recommended dose levels

Therapeutic Class

  • Second generation Cephalosporins

Reconstitution

  • Instructions for reconstituting for intramuscular and intravenous injections

Storage Conditions

  • Storage in a cool, dry place (below 30° C)
  • Protection from light and moisture
  • Keep out of the reach of children

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