Amovast 5 mg+10 mg (Tablet)
Unit Price: ৳ 11.07 (2 x 10: ৳ 221.40)
Strip Price: ৳ 110.70
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate atorvastatin |
Company | Beacon pharmaceuticals plc |
Title
- Amlodipine Besilate and Atorvastatin Calcium Tablets
Categories
- Hypertension Medication
- Anti-anginal Medication
- Lipid-lowering Medication
Description
- Combination product of Amlodipine Besilate and Atorvastatin Calcium
- Recommended for patients with hypertension, chronic stable angina, hypercholesterolemia
- Reduces risk of nonfatal myocardial infarction and nonfatal stroke
DosageForm
- Tablets
DosageStrength
- Amlodipine Besilate BP equivalent to 5 mg Amlodipine
- Atorvastatin calcium INN equivalent to 10 mg Atorvastatin
UsualInitialDose
- Amlodipine: 5 mg once daily
- Atorvastatin: 10 mg daily
MaximumDose
- Amlodipine: 10 mg once daily
- Atorvastatin: 80 mg once daily
AdministrationInstructions
- Amlodipine can be administered alone or in combination with other antihypertensive agents
SideEffects
- Amlodipine: Rarely reported acute hypotension
- Atorvastatin: Elevation in serum creatine phosphokinase levels, myalgia
Contraindications
- Hypersensitivity to Amlodipine
- Hypersensitivity to any component of Atorvastatin
- Active liver disease or unexplained persistent elevations of serum transaminases exceed three times the upper limit of normal
PregnancyLactationSafety
- Not recommended during pregnancy and breastfeeding
DrugInteraction
- Atorvastatin interaction with cyclosporine, fibric acid derivatives, niacin, erythromycin, azole antifungals
- Amlodipine may potentiate the effect of other antihypertensive agents
StorageConditions
- Store in a cool and dry place
- Protect from light and moisture
- Keep out of the reach of children
Pharmacology
- Amlodipine is a peripheral arterial vasodilator
- Atorvastatin is a synthetic lipid-lowering agent
PrecautionsWarnings
- Caution in administering Amlodipine to patients with severe aortic stenosis
- Use of all calcium channel blockers with caution in patients with heart failure
- Consider discontinuing Atorvastatin therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected
PediatricUse
- Safety and efficacy of Atorvastatin not established in children
GeriatricUse
- Efficacy and safety in older patients using recommended doses is similar to that seen in the general population
TherapeuticClass
- Anti-anginal & lipid lowering drugs