Cefstar 250 mg (Tablet)

Unit Price: ৳ 25.08 (8's pack: ৳ 200.64)

Medicine Details

Category	Details
Generic	Cefuroxime axetil
Company	Pharmadesh laboratories ltd
Also available as	Cefstar 125 mg tablet Cefstar 500 mg tablet Cefstar 125 mg suspension

Indications

Treatment of infections caused by sensitive bacteria
Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
Acute Bacterial Otitis Media caused by various bacteria
Acute bacterial maxillary sinusitis
Lower respiratory tract infections including pneumoniae
Skin and skin-structure infections
Urinary tract infections
Bone and Joint Infections
Gonorrhoea
Early Lyme Disease (erythema migrans)

Pharmacology

Cefuroxime is a well-characterized and effective antibacterial agent, which has broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains.

Dosage

Tablet or Suspension:
- Adolescents and adults (13 years and older):
  - Pharyngitis/tonsillitis
  - Acute bacterial maxillary sinusitis
  - Acute bacterial exacerbation of chronic bronchitis
  - Secondary bacterial infections of acute bronchitis
  - Uncomplicated skin and skin structure infections
  - Uncomplicated urinary tract infections
  - Uncomplicated Gonorrhoea
  - Community acquired pneumonia
  - MDR Typhoid Fever
  - Early Lyme disease
- Paediatric Patients (3 months to 12 years):
  - Pharyngitis/Tonsillitis
  - Acute otitis media
  - Acute bacterial maxillary sinusitis
  - Impetigo
Parenteral:
- Adult
- Children
- Neonate
- Surgical prophylaxis
- Pneumonia
- Acute exacerbations of chronic bronchitis
- In Gonorrhoea
- In Meningitis
- In bone and joint infections

Administration

The use of freshly reconstituted solution is recommended. It maintains potency for at least 24 hours at room temperature or 48 hours at 5o C.

Interaction

No potentially hazardous interactions reported.

Contraindications

Cefuroxime is contraindicated in patients with known allergy to Cephalosporins.

Side Effects

Adverse effects to Cefstar have occurred infrequently, including rashes and gastrointestinal disturbances. Prolonged use may result in the overgrowth of non-susceptible organisms e.g. Candida.

Pregnancy & Lactation

US FDA pregnancy category of Cefuroxime is B. Caution should be exercised when administered to a nursing woman.

Precautions & Warnings

Care should be given to patients receiving concurrent treatment with potent diuretics & who have a history of colitis. Cephalosporin antibiotics may be given safely to patients who are hypersensitive to penicillin although cross reactions have been reported.

Therapeutic Class

Second generation Cephalosporins

Reconstitution

For 750 mg intramuscular injection: Add 3 ml water for injection to vial and then shake gently for dispersion
For 750 mg intravenous injection: Add 8 ml water for injection to vial and then shake gently for dispersion. The solution should be slowly injected directly into a vein over a 3 to 5 minutes period
For 1.5 g intravenous injection: Add 16 ml Water for injection to vial and then shake gently for dispersion. The solution should be slowly injected directly into a vein over a 3 to 5 minutes period

Storage Conditions

Store in a cool, dry place (below 30o C), away from light & moisture. Keep out of the reach of children.