Cefstar 125 mg/5 ml (Powder for Suspension)

70 ml bottle: ৳ 190.00

Medicine Details

Category Details
Generic Cefuroxime axetil
Company Pharmadesh laboratories ltd
Also available as
Cefstar 125 mg tablet Cefstar 250 mg tablet Cefstar 500 mg tablet

Product Title

  • Cefuroxime Tablet

Categories

  • Antibiotics
  • Infectious Diseases
  • Respiratory Tract Infections
  • Skin Infections
  • Urinary Tract Infections
  • Bone and Joint Infections
  • Bacterial Infections

Description

  • Cefuroxime is a well-characterized and effective antibacterial agent with broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains. It is indicated for the treatment of infections caused by sensitive bacteria. Cefuroxime is contraindicated in patients with known allergy to Cephalosporins.

Color Options

  • White

Dimensions

  • Various tablet sizes available

Functions

  • Treats pharyngitis/tonsillitis
  • Treats acute otitis media
  • Treats acute bacterial maxillary sinusitis
  • Treats lower respiratory tract infections including pneumonia
  • Treats skin and skin-structure infections
  • Treats urinary tract infections
  • Treats bone and joint infections
  • Treats gonorrhea
  • Treats early Lyme disease
  • Acts as a surgical prophylaxis for high risk procedures

Materials

  • Cefuroxime

Technical Specifications

  • Broad-spectrum bactericidal activity
  • Good stability to bacterial β-lactamase
  • Active against many ampicillin-resistant and amoxycillin-resistant strains

Design Elements

  • Tablet or Suspension form
  • Reconstituted solution is recommended for parenteral administration

Usability Features

  • Suitable for adolescents, adults, and pediatric patients
  • Freshly reconstituted solution maintains potency for at least 24 hours at room temperature or 48 hours at 5<sup>o</sup> C

Dosage

  • Tablet or Suspension:
    • Adolescents and adults (13 years and older):
      • Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
      • Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
      • Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
      • Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
      • Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
      • Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
      • Uncomplicated Gonorrhoea: 1000 mg Single dose
      • Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
      • MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
      • Early Lyme disease: 500 mg b.i.d. for 20 days
    • Paediatric Patients (3 months to 12 years):
      • Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
      • Acute otitis media: 30 mg/kg/day b.i.d for 10 days
      • Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
      • Impetigo: 30 mg/kg/day b.i.d for 10 days
  • Parenteral:
    • Detailed dosage information for adults, children, neonates, and specific conditions such as pneumonia, acute exacerbations of chronic bronchitis, gonorrhoea, meningitis, and bone and joint infections

Storage Conditions

  • Store in a cool, dry place (below 30<sup>o</sup> C)
  • Away from light &amp; moisture
  • Keep out of the reach of children

Administration

  • Use of freshly reconstituted solution is recommended

Interaction

  • No potentially hazardous interactions reported

Side Effects

  • Adverse effects to Cefuroxime occurred infrequently and have been generally mild and transient in nature. Effects reported include rashes and gastrointestinal disturbances. Prolonged use may result in the overgrowth of non-susceptible organisms e.g. Candida.

Pregnancy & Lactation

  • US FDA pregnancy category of Cefuroxime is B. No adequate and well-controlled studies in pregnant women. Caution recommended during pregnancy. Excreted in human milk, caution advised when administered to a nursing woman.

Precautions & Warnings

  • Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics &amp; who have a history of colitis. Cephalosporin antibiotics may be given safely to patients who are hypersensitive to penicillin, although cross reactions have been reported.

Contraindications

  • Cefuroxime is contraindicated in patients with known allergy to Cephalosporins

Therapeutic Class

  • Second generation Cephalosporins

Reconstitution

  • Specific reconstitution instructions provided for intramuscular and intravenous injections

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