Famicef 125 mg/5 ml (Powder for Suspension)
70 ml bottle: ৳ 325.00
Medicine Details
Category | Details |
---|---|
Generic | Cefuroxime axetil |
Company | Acme laboratories ltd |
Also available as |
Indications
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
- Acute bacterial maxillary sinusitis
- Lower respiratory tract infections including pneumoniae
- Acute bacterial exacerbation of chronic bronchitis
- Secondary bacterial infections of Acute bronchitis
- Skin and skin-structure infections
- Urinary tract infections
- Bone and Joint Infections
- Gonorrhoea
- Early Lyme Disease (erythema migrans)
Pharmacology
Broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains
Dosage
- Tablet or Suspension:
- Adolescents and adults (13 years and older):
- Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
- Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
- Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
- Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
- Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
- Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
- Uncomplicated Gonorrhoea: 1000 mg Single dose
- Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
- MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
- Early Lyme disease: 500 mg b.i.d. for 20 days
- Paediatric Patients (3 months to 12 years):
- Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
- Acute otitis media: 30 mg/kg/day b.i.d for 10 days
- Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
- Impetigo: 30 mg/kg/day b.i.d for 10 days
- Adolescents and adults (13 years and older):
- Parenteral:
- Adult: 750 mg three times daily by IM or IV injection
- Children (above 3 months of age): 30 - 100 mg/kg/day given in 3 or 4 equally divided doses
- Neonate: 30 - 100 mg/kg/day given in 2 or 3 equally divided doses
- Surgical prophylaxis: 1.5 gm by IV injection at induction of anaesthesia; up to 3 further doses of 750 mg may be given by IV/IM injection every 8 hours for high risk procedures
Administration
The use of freshly reconstituted solution is recommended. It maintains potency for at least 24 hours at room temperature or 48 hours at 5°C
Interaction
No potentially hazardous interactions reported
Contraindications
Cefuroxime is contraindicated in patients with known allergy to Cephalosporins
Side Effects
- Rashes
- Gastrointestinal disturbances
- Overgrowth of non susceptible organisms e.g. Candida
Pregnancy & Lactation
US FDA pregnancy category of Cefuroxime is B. Caution should be exercised when Cefuroxime is administered to a nursing woman
Precautions & Warnings
Cephalosporins may be given safely to patients who are hypersensitive to penicillin although cross reactions have been reported
Therapeutic Class
Second generation Cephalosporins
Reconstitution
- For 750 mg intramuscular injection: Add 3 ml water for injection to vial and then shake gently for dispersion
- For 750 mg intravenous injection: Add 8 ml water for injection to vial and then shake gently for dispersion
- For 1.5 g intravenous injection: Add 16 ml Water for injection to vial and then shake gently for dispersion. The solution should be slowly injected directly into a vein over a 3 to 5 minutes period
Storage Conditions
Store in a cool, dry place (below 30°C), away from light & moisture