Furocef 125 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/Tonsillitis
- Acute bacterial otitis media
- Acute bacterial maxillary sinusitis
- Lower respiratory tract infections
- Skin and skin-structure infections
- Urinary tract infections
- Bone and joint infections
- Gonorrhoea
- Early Lyme Disease
Pharmacology
Cefuroxime is a well-characterized and effective antibacterial agent with broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains.
Dosage
- Tablet or Suspension:
- Adolescents and adults (13 years and older):
- Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
- Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
- Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
- Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
- Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
- Paediatric Patients (3 months to 12 years):
- Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
- Acute otitis media: 30 mg/kg/day b.i.d for 10 days
- Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
- Impetigo: 30 mg/kg/day b.i.d for 10 days
- Adolescents and adults (13 years and older):
- Parenteral:
- Recommended dosages for adults and children in various conditions and for surgical prophylaxis
Administration
The use of freshly reconstituted solution is recommended and it maintains potency for at least 24 hours at room temperature or 48 hours at 5<sup>o</sup> C.
Interaction
No potentially hazardous interactions reported.
Contraindications
Cefuroxime is contraindicated in patients with known allergy to Cephalosporins.
Side Effects
Adverse effects to Furocef have occurred infrequently and have been generally mild and transient in nature. Effects reported include rashes and gastrointestinal disturbances. Prolonged use may result in the overgrowth of non-susceptible organisms e.g. Candida.
Pregnancy & Lactation
- US FDA Pregnancy Category: B
- Guidance for Use During Pregnancy: Should be used during pregnancy only if clearly needed. Cefuroxime have been shown to be excreted in human milk. Caution should be exercised when Cefuroxime is administered to a nursing woman.
Precautions & Warnings
Furocef should be given with care to patients receiving concurrent treatment with potent diuretics & who has a history of colitis. Cross reactions with penicillin hypersensitivity have been reported. Furocef has shown it is not likely to be a problem at the recommended dose levels.
Therapeutic Class
Second generation Cephalosporins
Reconstitution
- For 750 mg intramuscular injection: Add 3 ml water for injection to vial and then shake gently for dispersion.
- For 750 mg intravenous injection: Add 8 ml water for injection to vial and then shake gently for dispersion. The solution should be slowly injected directly into a vein over a 3 to 5 minutes period.
- For 1.5 g intravenous injection: Add 16 ml water for injection to vial and then shake gently for dispersion. The solution should be slowly injected directly into a vein over a 3 to 5 minutes period.
Storage Conditions
Store in a cool, dry place (below 30<sup>o</sup> C), away from light & moisture. Keep out of the reach of children.