Furotec 500 mg (Tablet)

Unit Price: ৳ 45.00 (8's pack: ৳ 360.00)

Medicine Details

Category	Details
Generic	Cefuroxime axetil
Company	Apc pharma ltd

Indications

Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
Lower respiratory tract infections including pneumoniae caused by Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella spp., Staphylococcus aureus, E. coli
Acute bacterial exacerbation of chronic bronchitis and Secondary bacterial infections of Acute bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae or Haemophilus parainfluenzae
Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
Urinary tract infections caused by E.coli or Klebsiella pneumoniae
Bone and Joint Infections caused by Staphylococcus aureus
Gonorrhoea caused by Neisseria gonorrhoeae
Early Lyme Disease caused by Borrelia burgdorferi

Pharmacology

Cefuroxime is a well-characterized and effective antibacterial agent, which has broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains

Dosage

Tablet or Suspension:
- Adolescents and adults (13 years and older):
  - Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
  - Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
  - Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
  - Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
  - Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
  - Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
  - Uncomplicated Gonorrhoea: 1000 mg Single dose
  - Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
  - MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
  - Early Lyme disease: 500 mg b.i.d. for 20 days
- Paediatric Patients (3 months to 12 years):
  - Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
  - Acute otitis media: 30 mg/kg/day b.i.d for 10 days
  - Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
  - Impetigo: 30 mg/kg/day b.i.d for 10 days
Parenteral:
- Adult: 750 mg three times daily by IM or IV injection
- Children (above 3 months of age): 30 - 100 mg/kg/day given in 3 or 4 equally divided doses
- Neonate: 30 - 100 mg/kg/day given in 2 or 3 equally divided doses

Administration

The use of freshly reconstituted solution is recommended. However, it maintains potency for at least 24 hours at room temperature or 48 hours at 5o C

Interaction

No potentially hazardous interactions have been reported

Contraindications

Cefuroxime is contraindicated in patients with known allergy to Cephalosporins

Side Effects

Adverse effects to Furotec have occurred infrequently and have been generally mild and transient in nature. Effects reported include rashes and gastrointestinal disturbances. Prolonged use may result in the overgrowth of non susceptible organisms e.g. Candida

Pregnancy & Lactation

US FDA pregnancy category of Cefuroxime is B. Caution should be exercised when Cefuroxime is administered to a nursing woman

Precautions & Warnings

Furotec should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis. Cephalosporin antibiotics may in general be given safely to patients who are hypersensitive to penicillin although cross reactions have been reported

Therapeutic Class

Second generation Cephalosporins

Reconstitution

For 750 mg intramuscular injection: Add 3 ml water for injection to vial and then shake gently for dispersion
For 750 mg intravenous injection: Add 8 ml water for injection to vial and then shake gently for dispersion
For 1.5 g intravenous injection: Add 16 ml Water for injection to vial and then shake gently for dispersion

Storage Conditions

Store in a cool, dry place (below 30o C), away from light & moisture. Keep out of the reach of children