Furotixol 125 mg/5 ml (Powder for Suspension)

70 ml bottle: ৳ 198.60

Medicine Details

Category	Details
Generic	Cefuroxime axetil
Company	Sharif pharmaceuticals ltd
Also available as	Furotixol 250 mg tablet Furotixol 500 mg tablet

Title

Cefuroxime Tablet

Description

Cefuroxime is an antibacterial agent used for the treatment of infections caused by sensitive bacteria, including pharyngitis, otitis media, sinusitis, pneumonia, bronchitis, skin and skin-structure infections, urinary tract infections, bone and joint infections, gonorrhea, and lyme disease.

DosageForm

Tablet, Suspension

AgeGroupDosage

Adolescents, Adults, Paediatric Patients, Neonates

DosageAdministrationRoutes

Oral
Intramuscular
Intravenous

DosageInstructions

AdolescentsAdults:
- PharyngitisTonsillitis:
  - 250 mg b.i.d. for 5-10 days
- AcuteBacterialMaxillarySinusitis:
  - Dosage: 250 mg b.i.d. for 10 days
- AcuteBacterialExacerbationChronicBronchitis:
  - 250-500 mg b.i.d. for 10 days
- SecondaryBacterialInfectionsAcuteBronchitis:
  - 250-500 mg b.i.d. for 5-10 days
- UncomplicatedSkinInfections:
  - 250-500 mg b.i.d. for 10 days
- UncomplicatedUrinaryTractInfections:
  - 250 mg b.i.d. for 7-10 days
- UncomplicatedGonorrhea:
  - 1000 mg Single dose
- CommunityAcquiredPneumonia:
  - 250-500 mg b.i.d. for 5-10 days
- MDRTyphoidFever:
  - 500 mg b.i.d. for 10-14 days
- EarlyLymeDisease:
  - 500 mg b.i.d. for 20 days
PaediatricPatients:
- PharyngitisTonsillitis:
  - 20 mg/kg/day b.i.d for 5-10 days
- AcuteOtitisMedia:
  - 30 mg/kg/day b.i.d for 10 days
- AcuteBacterialMaxillarySinusitis:
  - 30 mg/kg/day b.i.d for 10 days
- Impetigo:
  - 30 mg/kg/day b.i.d for 10 days
Parenteral:
- Adult:
  - 750 mg three times daily by IM or IV injection
- Children:
  - 30 - 100 mg/kg/day given in 3 or 4 equally divided doses
- Neonate:
  - 30 - 100 mg/kg/day given in 2 or 3 equally divided doses
- SurgicalProphylaxis:
  - 1.5 gm by IV injection at induction of anaesthesia
- Pneumonia:
  - 1.5 gm IV injection twice daily for 2-3 days
- AcuteExacerbationsChronicBronchitis:
  - 750 mg twice daily (IM or IV injection) for 2-3 days
- Gonorrhea:
  - 1.5 gm as a single dose
- Meningitis:
  - Adult:
    - 3 gm IV injection three times daily
  - Children:
    - 200-240 mg/kg/day by IV injection in 3 or 4 divided doses reduced to 100 mg/kg/day after 3 days or on clinical improvement
  - Neonate:
    - 100 mg/kg/day by IV injection
- BoneJointInfections:
  - Adult:
    - 1.5 gm IV injection four times daily
  - Children:
    - 150 mg/kg/day in equally divided doses every 8 hours

AdministrationRecommendation

Use freshly reconstituted solution

PotencyStability

Maintains potency for at least 24 hours at room temperature or 48 hours at 5°C

Interaction

No potentially hazardous interactions reported

Contraindications

Known allergy to Cephalosporins

SideEffects

Common:
- Rashes
- Gastrointestinal disturbances
LongTermUse:
- Overgrowth of non-susceptible organisms (e.g., Candida)

PregnancyLactation

FDA PregnancyCategory: B
PregnancyUse: Only if clearly needed
LactationCaution: Excreted in human milk, caution advised

PrecautionsWarnings

SpecialCarePatients:
- ReceivingTreatment:
  - Potent diuretics
- WithHistoryOf:
  - Colitis
CephalosporinHypersensitivity:
- CrossReactions:
  - Reported, but less likely at recommended doses

TherapeuticClass

Second generation Cephalosporins

ReconstitutionInstructions

IntramuscularInjection750mg: Add 3 ml water for injection to vial and shake gently for dispersion
IntravenousInjection750mg: Add 8 ml water for injection to vial and shake gently for dispersion
IntravenousInjection15g: Add 16 ml Water for injection to vial and shake gently for dispersion

StorageConditions

Store in a cool, dry place (below 30°C)
Away from light & moisture
Keep out of the reach of children