Kfore 500 mg (Tablet)
Unit Price: ৳ 45.13 (8's pack: ৳ 361.04)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Kemiko pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
- Lower respiratory tract infections including pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella spp., Staphylococcus aureus, E. coli
- Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
- Urinary tract infections caused by E.coli or Klebsiella pneumoniae
- Bone and Joint Infections caused by Staphylococcus aureus
- Gonorrhoea caused by Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
- Acute bacterial exacerbation of chronic bronchitis
- Secondary bacterial infections of Acute bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae
Pharmacology
- Broad-spectrum bactericidal activity
- Effective against β-lactamase producing strains
- Good stability to bacterial β-lactamase
Dosage
- 250 mg b.i.d. for adolescents and adults (Pharyngitis/Tonsillitis)
- 250 mg b.i.d. for 10 days in Acute bacterial maxillary sinusitis
- 250-500 mg b.i.d. for 10 days in Acute bacterial exacerbation of chronic bronchitis
- 250-500 mg b.i.d. for 5-10 days in Secondary bacterial infections of Acute bronchitis
- 750 mg three times daily for adults by IM or IV injection
- 30 - 100 mg/kg/day for children above 3 months of age
Administration
- Use of freshly reconstituted solution recommended
- Maintains potency for at least 24 hours at room temperature or 48 hours at 5°C
Interaction
- No potentially hazardous interactions reported
Contraindications
- Contraindicated in patients with known allergy to Cephalosporins
Side Effects
- Adverse effects occurred infrequently
- Reported effects include rashes and gastrointestinal disturbances
- Prolonged use may result in overgrowth of non-susceptible organisms
Pregnancy & Lactation
- US FDA pregnancy category B
- No adequate and well-controlled studies in pregnant women
- Excreted in human milk
Precautions & Warnings
- Given with care to patients receiving concurrent treatment with potent diuretics
- Cephalosporin antibiotics may be given safely to patients hypersensitive to penicillin
- Cross reactions have been reported
Therapeutic Class
- Second generation Cephalosporins
Reconstitution
- For 750 mg intramuscular injection: Add 3 ml water for injection to vial and then shake gently for dispersion
- For 750 mg intravenous injection: Add 8 ml water for injection to vial and then shake gently for dispersion
- For 1.5 g intravenous injection: Add 16 ml water for injection to vial and then shake gently for dispersion
Storage Conditions
- Store in a cool, dry place (below 30°C)
- Away from light & moisture
- Keep out of reach of children