Mextil 125 mg/5 ml (Powder for Suspension)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Biopharma limited |
| Also available as |
Indications
- Treatment of Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Treatment of Acute Bacterial Otitis Media caused by various bacteria
- Treatment of Acute bacterial maxillary sinusitis caused by specific bacteria
- Treatment of Lower respiratory tract infections including pneumonia caused by various bacteria
- Treatment of Acute bacterial exacerbation of chronic bronchitis and Secondary bacterial infections of Acute bronchitis caused by specific bacteria
- Treatment of Skin and skin-structure infections caused by specific bacteria
- Treatment of Urinary tract infections caused by specific bacteria
- Treatment of Bone and Joint Infections caused by specific bacteria
- Treatment of Gonorrhoea caused by specific strains of Neisseria gonorrhoeae
- Treatment of Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
Pharmacology
Cefuroxime is a well-characterized and effective antibacterial agent with broad-spectrum bactericidal activity against a wide range of common pathogens, including beta-lactamase producing strains.
Dosage
- Tablet or Suspension:
- Adolescents and adults (13 years and older):
- Dosage for Pharyngitis/tonsillitis
- Dosage for Acute bacterial maxillary sinusitis
- Dosage for Acute bacterial exacerbation of chronic bronchitis
- Dosage for Secondary bacterial infections of acute bronchitis
- Dosage for Uncomplicated skin and skin structure infections
- Dosage for Uncomplicated urinary tract infections
- Dosage for Uncomplicated Gonorrhoea
- Dosage for Community acquired pneumonia
- Dosage for MDR Typhoid Fever
- Dosage for Early Lyme disease
- Paediatric Patients (3 months to 12 years):
- Dosage for Pharyngitis/Tonsillitis
- Dosage for Acute otitis media
- Dosage for Acute bacterial maxillary sinusitis
- Dosage for Impetigo
- Adolescents and adults (13 years and older):
- Parenteral:
- Dosage for Adult
- Dosage for Children (above 3 months of age)
- Dosage for Neonate
- Dosage for Surgical prophylaxis
- Dosage for Pneumonia
- Dosage for Acute exacerbations of chronic bronchitis
- Dosage in Gonorrhoea
- Dosage in Meningitis
- Dosage in bone and joint infections
Administration
The use of freshly reconstituted solution is recommended. It maintains potency for at least 24 hours at room temperature or 48 hours at 5°C.
Interaction
No potentially hazardous interactions reported.
Contraindications
Cefuroxime is contraindicated in patients with known allergy to Cephalosporins.
Side Effects
Adverse effects to Cefuroxime have occurred infrequently and have been generally mild and transient in nature. Effects reported include rashes and gastrointestinal disturbances. Prolonged use may result in the overgrowth of non-susceptible organisms e.g. Candida.
Pregnancy & Lactation
US FDA pregnancy category of Cefuroxime is B. Caution should be exercised when Cefuroxime is administered to a nursing woman.
Precautions & Warnings
Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis. Cross reactions with penicillin have been reported.
Therapeutic Class
Second generation Cephalosporins
Reconstitution
Instructions for reconstitution of intramuscular and intravenous injections
Storage Conditions
Store in a cool, dry place (below 30°C), away from light & moisture. Keep out of the reach of children.