Mextil DS 250 mg/5 ml (Powder for Suspension)
50 ml bottle: ৳ 250.94
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Biopharma limited |
| Also available as |
Indications
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
- Lower respiratory tract infections including pneumoniae
- Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
- Urinary tract infections caused by E.coli or Klebsiella pneumoniae
- Bone and Joint Infections caused by Staphylococcus aureus
- Gonorrhoea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
Pharmacology
- Broad-spectrum bactericidal activity
- Good stability to bacterial β-lactamase
- Active against many ampicillin-resistant and amoxycillin-resistant strains
Dosage
- Suitable dosages for adolescents, adults, and pediatric patients
- Different dosages for various infections including pharyngitis, otitis media, urinary tract infections, and pneumonia
- Instructions for tablet/suspension and parenteral dosages
Administration
Use of freshly reconstituted solution recommended
Interaction
No potentially hazardous interactions reported
Contraindications
Contraindicated in patients with known allergy to Cephalosporins
Side Effects
- Occasional rashes and gastrointestinal disturbances
- Prolonged use may result in overgrowth of non-susceptible organisms
Pregnancy & Lactation
- US FDA pregnancy category B
- Excreted in human milk
- Caution advised for use during pregnancy and nursing
Precautions & Warnings
- Given with care to patients receiving concurrent treatment with potent diuretics
- Caution advised for patients with a history of colitis
- Use with caution in patients hypersensitive to penicillin
- Cross reactions reported between cephalosporin antibiotics and penicillin
Therapeutic Class
Second generation Cephalosporins
Reconstitution
Instructions for reconstitution for different injection strengths
Storage Conditions
Store in cool, dry place away from light and moisture, below 30°C