Sefur 750 mg/vial (IM/IV Injection)

750 mg vial: ৳ 150.00

Medicine Details

Category Details
Generic Cefuroxime axetil
Company Opsonin pharma ltd
Also available as
Sefur 125 mg tablet Sefur 250 mg tablet Sefur 500 mg tablet Sefur 125 mg suspension Sefur ds 250 mg suspension Sefur 15 gm injection

Indications

  • Treatment of infections caused by sensitive bacteria
  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
  • Lower respiratory tract infections including pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella spp., Staphylococcus aureus, E. coli
  • Acute bacterial exacerbation of chronic bronchitis and Secondary bacterial infections of Acute bronchitis
  • Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
  • Urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus
  • Gonorrhoea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi

Pharmacology

  • Broad-spectrum bactericidal activity
  • Effective against beta-lactamase producing strains
  • Good stability to bacterial beta-lactamase
  • Active against many ampicillin-resistant and amoxycillin-resistant strains

Dosage

  • Different dosages for adolescents and adults
  • Dosage for pharyngitis/tonsillitis, acute bacterial maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, secondary bacterial infections of acute bronchitis, uncomplicated skin and skin structure infections, uncomplicated urinary tract infections, uncomplicated Gonorrhoea, community acquired pneumonia, MDR Typhoid Fever, and early Lyme disease

Administration

Use of freshly reconstituted solution is recommended

Interaction

No potentially hazardous interactions reported

Contraindications

Contraindicated in patients with known allergy to Cephalosporins

Side Effects

  • Adverse effects occurred infrequently
  • Mild and transient effects reported
  • Rashes and gastrointestinal disturbances reported
  • Prolonged use may result in overgrowth of non-susceptible organisms e.g. Candida

Pregnancy & Lactation

US FDA pregnancy category of Cefuroxime is B

Precautions & Warnings

Care needed for patients receiving concurrent treatment with potent diuretics & with a history of colitis

Therapeutic Class

Second generation Cephalosporins

Reconstitution

Specific reconstitution instructions for different types of injections

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture

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