Turbocef 1.5 gm/vial (IV Injection)

1.5 gm vial: ৳ 200.00

Medicine Details

Category Details
Generic Cefuroxime axetil
Company Beximco pharmaceuticals ltd
Also available as
Turbocef 250 mg tablet Turbocef 500 mg tablet Turbocef 125 mg suspension Turbocef 750 mg injection

Indications

  • Treatment of infections caused by sensitive bacteria
  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
  • Lower respiratory tract infections including pneumoniae, caused by Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella spp., Staphylococcus aureus, E. coli
  • Acute bacterial exacerbation of chronic bronchitis and Secondary bacterial infections of Acute bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae or Haemophilus parainfluenzae
  • Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
  • Urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus
  • Gonorrhoea caused by Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi

Pharmacology

  • Broad-spectrum bactericidal activity
  • Effective against β-lactamase producing strains
  • Good stability to bacterial β-lactamase
  • Active against many ampicillin-resistant and amoxycillin-resistant strains

Dosage

  • Tablet or Suspension:
    • Adolescents and adults (13 years and older)
    • Pediatric Patients (3 months to 12 years)
  • Parenteral:
    • Adult
    • Children (above 3 months of age)
    • Neonate
  • Meningitis:
    • Adult
    • Children (above 3 months of age)
    • Neonate
  • Bone and joint infections:
    • Adult
    • Children (above 3 months of age)

Administration

Use of freshly reconstituted solution is recommended

Interaction

No potentially hazardous interactions reported

Contraindications

Patients with known allergy to Cephalosporins

Side Effects

  • Infrequent and generally mild
  • Transient in nature
  • Rashes
  • Gastrointestinal disturbances
  • Prolonged use may result in overgrowth of non susceptible organisms e.g. Candida

Pregnancy & Lactation

  • US FDA pregnancy category B
  • No adequate and well-controlled studies in pregnant women
  • Excreted in human milk
  • Caution when administered to a nursing woman

Precautions & Warnings

  • Given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis
  • Cephalosporin antibiotics may be given safely to patients who are hypersensitive to penicillin
  • Cross reactions reported
  • Not likely to be a problem at the recommended dose levels

Therapeutic Class

Second generation Cephalosporins

Reconstitution

  • For 750 mg intramuscular injection
  • For 750 mg intravenous injection
  • For 1.5 g intravenous injection

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture

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