Uroxime 125 mg/5 ml (Powder for Suspension)

70 ml bottle: ৳ 198.00

Medicine Details

Title

  • Uroxime Tablets

Category

  • Antibiotics
  • Medication

DosageForm

  • Tablet
  • Suspension
  • Injection

AgeGroup

  • Adults
  • Adolescents
  • Children
  • Neonates

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae, Haemophilus influenzae
  • Lower respiratory tract infections including pneumoniae caused by various bacteria
  • Skin and skin-structure infections caused by Staphylococcus aureus, Streptococcus pyogenes
  • Urinary tract infections caused by E.coli, Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus
  • Gonorrhoea caused by Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi

Pharmacology

  • Broad-spectrum bactericidal activity
  • Good stability to bacterial β-lactamase

Dosage

  • 250 mg b.i.d. for 5-10 days (Adolescents and adults)
  • 20 mg/kg/day b.i.d for 5-10 days (Paediatric Patients)
  • 750 mg three times daily by IM or IV injection (Adults)
  • 30 - 100 mg/kg/day given in 3 or 4 equally divided doses (Children above 3 months of age)

Administration

  • Use freshly reconstituted solution recommended
  • Maintains potency for at least 24 hours at room temperature or 48 hours at 5°C

Interaction

  • No potentially hazardous interactions reported

Contraindications

  • Known allergy to Cephalosporins

SideEffects

  • Rashes
  • Gastrointestinal disturbances
  • Prolonged use may result in the overgrowth of non-susceptible organisms e.g. Candida

PregnancyAndLactation

  • US FDA pregnancy category B
  • Cautious use during pregnancy and lactation

PrecautionsAndWarnings

  • Careful use with concurrent treatment with potent diuretics
  • History of colitis
  • Cross reactions reported for hypersensitivity to penicillin

TherapeuticClass

  • Second generation Cephalosporins

Reconstitution

  • Specific reconstitution instructions for different injection dosages

StorageConditions

  • Store in a cool, dry place below 30°C
  • Away from light and moisture
  • Keep out of the reach of children

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