Xorimax 500 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Sandoz a novartis division |
| Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by various bacteria
- Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
- Urinary tract infections caused by E. coli or Klebsiella pneumoniae
- Gonorrhoea caused by Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
Pharmacology
Broad-spectrum bactericidal activity against a wide range of common pathogens, good stability to bacterial β-lactamase
Dosage
- Tablet or Suspension:
- Adolescents and adults (13 years and older): 250 mg b.i.d. for various durations based on infection type
- Paediatric Patients (3 months to 12 years): Dose based on infection type and weight
- Parenteral:
- Adult: 750 mg-1.5 gm three times daily by IM or IV injection
- Children (above 3 months of age): 30 - 100 mg/kg/day given in 3 or 4 equally divided doses
Administration
Use of freshly reconstituted solution is recommended, maintains potency for at least 24 hours at room temperature or 48 hours at 5<sup>o</sup> C
Interaction
No potentially hazardous interactions reported
Contraindications
Contraindicated in patients with known allergy to Cephalosporins
Side Effects
Rashes, gastrointestinal disturbances, overgrowth of non susceptible organisms
Pregnancy & Lactation
US FDA pregnancy category of Cefuroxime is B, caution during pregnancy and lactation
Precautions & Warnings
Care for patients receiving concurrent treatment with potent diuretics, caution for nursing women
Therapeutic Class
Second generation Cephalosporins
Reconstitution
Instructions for reconstituting for intramuscular and intravenous injection
Storage Conditions
Store in a cool, dry place (below 30<sup>o</sup> C), away from light & moisture