Clavusef 125 mg+31.25 mg (Tablet)

Unit Price: ৳ 20.00 (4 x 4: ৳ 320.00)
Strip Price: ৳ 80.00

Medicine Details

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
  • Lower respiratory tract infections including pneumoniae
  • Acute bacterial exacerbation of chronic bronchitis and secondary bacterial infections of Acute bronchitis
  • Uncomplicated skin and skin-structure infections
  • Uncomplicated urinary tract infections
  • Bone and Joint Infections
  • Uncomplicated Gonorrhoea
  • Early Lyme Disease (erythema migrans)
  • Septicemia
  • Meningitis
  • Switch therapy (Injectable to oral)

Pharmacology

  • Bactericidal
  • Interferes with transpeptidation process
  • Inhibits bacterial cell wall synthesis
  • Protection from degradation by beta lactamase enzymes

Dosage & Administration

  • 250-500 mg b.i.d.
  • 7-14 days duration
  • May be taken without regard of food
  • Pediatric dosage based on weight
  • Single dose for certain indications

Interaction

Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Renal dysfunction
  • Anaphylaxis
  • Angioedema
  • Pruritis
  • Rash
  • Serum sickness like urticaria

Pregnancy & Lactation

Can be safely used in later pregnancy to treat urinary and other infections

Precautions & Warnings

  • Given with care to patients receiving concurrent treatment with potent diuretics
  • History of colitis

Therapeutic Class

Second generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light and moisture

Common Questions

  • Starts working within 2-3 hours
  • Lasts for an average duration of 4-8 hours
  • Safety with alcohol consumption is unknown
  • Not habit forming
  • Safe to use during pregnancy
  • Safe to use during breastfeeding
  • Take medicine with food to avoid upset stomach
  • Stop taking if itchy rash, swelling, or breathing difficulties occur
  • Do not use leftover medicine for future infections

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